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复方降脂胶囊对高脂血症大鼠脂代谢的影响
引用本文:王艳苹,王国文,孙伟.复方降脂胶囊对高脂血症大鼠脂代谢的影响[J].国际中医中药杂志,2007,29(2):70-72.
作者姓名:王艳苹  王国文  孙伟
作者单位:1. 157011,牡丹江,牡丹江医学院附属红旗医院老年病科
2. 157011,牡丹江,牡丹江解放军209医院医务科
3. 157011,牡丹江,牡丹江医学院附属红旗医院科研处
摘    要:目的 探讨复方降脂胶囊对高脂血症大鼠脂代谢的影响。方法 采用高脂饮食法建立高脂血症大鼠模型。治疗组给予复方降脂胶囊,对照组给予血脂康,观察治疗后血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)的变化,并观察肝脏的组织学变化。结果 复方降脂胶囊能显著降低高脂血症大鼠血清TC、TG、LDL水平(P〈0.01),且优于血脂康对照组(P〈0.05)。病理学表明,复方降脂胶囊治疗组大鼠肝脏无明显脂肪变性。结论 复方降脂胶囊可降低血脂,减轻肝脏脂肪变性。

关 键 词:复方降脂胶囊  高脂血症  大鼠
修稿时间:2006-12-21

Experimental Study of the Effect of Jiangzhi Compound Capsule on Lipid Metabolism in Rats Model of Hyperlipidemia
WANG Yan-ping,WANG Guo-wen,SUN Wei.Experimental Study of the Effect of Jiangzhi Compound Capsule on Lipid Metabolism in Rats Model of Hyperlipidemia[J].International Journal of Traditional Chinese Medicine,2007,29(2):70-72.
Authors:WANG Yan-ping  WANG Guo-wen  SUN Wei
Affiliation:Department of elderly diseases, Honeai Hospital of Mudanjiang Medical college. Mudanjiang,157011 China
Abstract:Objective To study the effect of Jiangzhi Compound capsule in treating hyperlipidemia in rats models. Methods The rat model of hyperlipidemia was established with high fat diet. The effect of Jiangzhi Compound capsule upon the serum total triglyceride(TG),cholestero(lTC),high density lipoprotein (HDL), and low density lipoprotein(LDL) was observed and contrasted with Xuezhikang. And the pathological changes of liver tissue were also observed. Results Compared with the Xuezhikang group, serum levels of TG,TC and LDL were all significantly decreased and no remarkably changes of fatty liver were observed in the Jiangzhi Compound Capsule group( p<0.05). Conclusions Jiangzhi Compound Capsule can obviously reduce blood lipid and decrease the pathological changes.
Keywords:Jiangzhi compound capsule  Hyperlipidemia  Experimental study
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