| 新的肾功能显像剂~（99m）锝—双半胱氨酸的临床研究 |
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| 引用本文： | 刘蕴忠,刘秀杰,张卫和,张正,朱霖,陈大舟,吴清文,刘华平,郭风,王道宇.新的肾功能显像剂~（99m）锝—双半胱氨酸的临床研究[J].中国循环杂志,1994(5). |
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| 作者姓名： | 刘蕴忠 刘秀杰 张卫和 张正 朱霖 陈大舟 吴清文 刘华平 郭风 王道宇 |
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| 作者单位： | 中国医学科学院心血管病研究所阜外医院，国家标准物质研究中心 |
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| 摘 要： | 一个新的肾功能显像剂９９ｍ锡一双半胱氨酸（９９Ｔｃ－ＥＣ）首先在国内研制成功，并进行了临床研究。结果表明：９９ｍＴｃ－ＥＣ的肾动态显像的２０ｍｉｎ清除率明显高于９９ｍＴｃ－ＤＴＰＡ。与数字减影血管造影（ＤＳＡ）比较，其对肾血管性高血压病的诊断符合率达到９０％以上。９９ｍＴｃ－ＥＣ是一种肾小管排泌型的药物，９９ｍＴｃ－ＤＴＰＡ是肾小球过滤型药物。在临床上二者互相补充，可更好地如实反映肾脏功能的情况。
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| 关 键 词： | ~（99m）锝—双半胱氨酸 肾功能显像剂 |
A NEW IMAGING AGENT-~(99m)Tc-EC FOR RENAL FUNCTION TEST |
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| Liu Yun-Zhong,Zhu Lin,Zhang Zheng,et al..A NEW IMAGING AGENT-~(99m)Tc-EC FOR RENAL FUNCTION TEST[J].Chinese Circulation Journal,1994(5). |
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| Authors: | Liu Yun-Zhong Zhu Lin Zhang Zheng |
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| Abstract: | The biological behavior of 99mTechnetium-L,Lethylenedicysteine(99mTc-EC) was studied in human(n=38) and compared with 99mTechnetium-diethylenetriamine pentacetic acid(99mTc-DTPAI.99mTc-EC,being an imaging agent for tubular excretion showed a more rapid urinary excretion than 99m Tc-DTPA which is an imaging agent for glomerular filtration.The results revealed higher 20 min clearance of 99mTc-EC and the image got by which was superior than that by 99mTc-DTPA.The combined use of both agents could reflect kidney function much better. |
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| Keywords: | ?99m)Tc-EC Renal function Imaging agent |
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