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直肠指检对前列腺良恶性疾病血清前列腺特异抗原的影响
引用本文:谷欣权,马庆杰,孔祥波,张刚,刚黎生,曹霞.直肠指检对前列腺良恶性疾病血清前列腺特异抗原的影响[J].中国老年学杂志,2003,23(3):162-163.
作者姓名:谷欣权  马庆杰  孔祥波  张刚  刚黎生  曹霞
作者单位:1. 吉林大学中日联谊医院泌尿外科,吉林,长春,130031
2. 吉林大学中日联谊医院核医学科
3. 梅河口市医院外科
4. 吉林大学中日联谊医院中心实验室
摘    要:目的:探讨直肠指检对前列腺增生(BPH)与前列腺癌(PCa)患者血清前列腺特异抗原(PSA)的影响。方法:应用时间分辨荧光免疫分析法,分别于直肠指检前和直肠指检后1d,3d,5d,7d检测BPH组25例与PCa组23例患者的血清FPSA,TPSA及F/T值,结果:两组患者血清FPSA,TPSA及PCa组患者F/T值在直肠指检后1d升高,与直肠指检前比较差别有显著性意义(P<0.01),3d后各项指标恢复至直肠指检前水平,结论:直肠指检对前列腺增生和前列腺癌患者血清PSA有一定的影响,PSA检测应在直肠指检前或直肠指检3-5d后进行。

关 键 词:前列腺特异抗原  前列腺增生  前列腺癌
文章编号:1005-9202(2003)03-0162-02
修稿时间:2002年7月1日

The effect of digital rectal examination on PSA in benign and malignant prostatic diseases
GU Xin quan,CAO Xia,MA Qing jie,et al.The effect of digital rectal examination on PSA in benign and malignant prostatic diseases[J].Chinese Journal of Gerontology,2003,23(3):162-163.
Authors:GU Xin quan  CAO Xia  MA Qing jie  
Abstract:Objective To evaluate the effect of digital rectal examination on serum PSA in benign and malignant prostatic diseases Methods The serum FPSA,TPSA and F/T ratio in 25 case of BPH patients and 23 case of PCa patients were measured by means of DELFIA method before and after digital rectal examination Results The levels of serum FPSA and TPSA in both groups and F/T ratio in PCa group increased in the first day after digital rectal examination( P <0 05), decreased to the initial levels in the third day after digital rectal examination Conclusions Digital rectal examination has some influence on serum PSA in BPH and PCa patients and the measurement of PSA should be done before or after digital rectal examination for 3 to 5 days
Keywords:Prostate specific antigen  Benign prostatic hyperplasia  Prostatic carcinoma
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