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心肺运动试验中窦房结变时效应频率应答特性的初步探讨
引用本文:钱卫民,冯建章,尹滔业,姚桦,伍彩英.心肺运动试验中窦房结变时效应频率应答特性的初步探讨[J].中国心脏起搏与心电生理杂志,1997(1).
作者姓名:钱卫民  冯建章  尹滔业  姚桦  伍彩英
作者单位:广东省心血管病研究所,广东人民医院
摘    要:采用最大症状限制性心肺运动试验的方法,依据运动过程中心率与机体作功和体内代谢强度的变化关系研究40名正常人运动中窦房结变时效应的频率应答特性,探讨心率储备和影响最大心率的主要因素。结果显示:心率与作功呈直线相关(Y=75+0.41X,r=0.9863,P<0.001)。运动中心率与代谢当量亦呈直线相关(Y=52.3+11.01X,r=0.9152,P<0.001)。影响最大心率的主要因素是氧耗量、二氧化碳量和每分通气量。运动过程中心率与运动负荷和代谢的线性关系反映了窦房结频率应答的特性,即代谢性频率应答。窦房结的这种特性可能是单传感器频率应答性起搏器不能完全符合生理需要的基本原因。

关 键 词:窦房结  变时效应  频率应答  心肺运动试验

The Study of Chronotropic Responsiveness of Sinus Node to Exercise Testing
Qian Weiming,Feng Jianzhang,Yin Taoye,et al.The Study of Chronotropic Responsiveness of Sinus Node to Exercise Testing[J].Chinese Journal of Cardiac Pacing and Electrophysiology,1997(1).
Authors:Qian Weiming  Feng Jianzhang  Yin Taoye  
Abstract:This study was to explore the chronotropic responsiveness of sinus node to workload and METS during cardiopulmanory exercise testing.Forty persons underwent symptomatic limited exercise testing.The relationship between heart rate and METS,heart rate and workload were analyzed with standard linear regression analysis.The major factors which might influnce heart rate were analyzed with multiple linear regression analysis.The results show:(1)There was a highly linear relation between heart rate and workload( Y =75 0.41 X , r =0.9863, P < 0.001) .There was also a linear relation between heart rate and METS( Y =52.3 11.01 X , r =0.9512, P < 0.001 ).The major factors which determined HR max during exercise were V CO 2max ,V O 2max and V E max .The chronotropic response of sinus node to exercise is the rate response which is controlled by metablism during exercise testing.This is the reason why the rate responsive pacemaker by one sensor is not suitable for the physiologic demand completely.
Keywords:Sinus node  Chronotropic response  Rate response  Cardiopulmonary exercise testing  
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