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Evaluating risk for alcohol use disorder: Polygenic risk scores and family history
Authors:Dongbing Lai  Emma C Johnson  Sarah Colbert  Gayathri Pandey  Grace Chan  Lance Bauer  Meredith W Francis  Victor Hesselbrock  Chella Kamarajan  John Kramer  Weipeng Kuang  Sally Kuo  Samuel Kuperman  Yunlong Liu  Vivia McCutcheon  Zhiping Pang  Martin H Plawecki  Marc Schuckit  Jay Tischfield  Leah Wetherill  Yong Zang  Howard J Edenberg  Bernice Porjesz  Arpana Agrawal  Tatiana Foroud
Affiliation:1. Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA;2. Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA;3. Henri Begleiter Neurodynamics Lab, Department of Psychiatry, Downstate Medical Center, State University of New York, Brooklyn, New York, USA;4. Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut, USA;5. The Brown School of Social Work, Washington University School of Medicine, St Louis, Missouri, USA;6. Department of Psychiatry, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA;7. Department of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA;8. Department of Neuroscience and Cell Biology, Child Health Institute of New Jersey, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA;9. Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA;10. Department of Psychiatry, University of California, San Diego Medical School, San Diego, California, USA;11. Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, New Jersey, USA;12. Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA
Abstract:
Keywords:alcohol use disorders  DSM-5 alcohol use disorder diagnostic criterion count  family history of AUD  polygenic risk scores
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