准分子激光屈光性角膜切削术后眼压测量值的变化

目的：探讨影响准分子激光屈光性角膜切削术（laser photorefractive keratectomy,PRK)后眼压测量值变化的因素。方法：对209例（364只眼）近视患者行PRK,手术前、后采用Goldemann压平式眼压计测量患者的眼压,并测量角膜厚度和角膜曲率,进行量角膜厚度和角膜曲率,进行统计学分析。术后随访时间＞1年。结果：术后6个月和12个月术眼的眼压测量值低于术前,差异有非常显著意义（P＜0．001）,术后12个月的眼压测量值低于术后6个月,差异有非常显著意义（P＜0．001）,术后12个月的眼压测量值低于术后6个月,差异有非常显著意义（P＜0．001）。术后眼压测量值的降低与角膜厚度的减少和角膜曲率的降低均呈高度正相关（P＜0．01）,其二元回归方程为Y（手术前、后眼压差,mmHg）＝1．156＋0．022X1（手术前、后角膜厚度差,μm)＋0．052X2（手术前、后角膜曲率差,D）。结论：PRK术后眼压测量值低于术前;角膜厚度和角膜曲率是导致手术前、后眼压测量值变化的因素。

Analysis of intraocular pressure after myopic photorefractive keratectomy

OBJECTIVE: To explore the factors related to intraocular pressure (IOP) after excimer laser photorefractive keratectomy (PRK). METHODS: Two hundred and nine cases (364 eyes) of myopia were studied with Goldmann applanation tonometer. All the patients were followed up for 12 months. RESULTS: After PRK, a decrease was observed in the IOP. The IOP reading in the 12(th) month was lower than that in the 6(th) month (P < 0.001). A positive correlation was found between IOP and corneal thickness or corneal curvature (r = 0.172, P < 0.001, r = 0.182, P < 0.001). Regression equation for IOP drop (mmHg) = 1.156 + 0.22X(1) + 0.052X(2), X(1) = decrease in corneal thickness ( micro m), X(2) = decrease in corneal curvature (D)]. CONCLUSION: The IOP measured after PRK for myopia is influenced by the corneal thickness, corneal curvature and steroid.