神经内科住院患者神经眼科临床特征研究

目的:研究神经内科患者神经眼科临床方面的基本特征,为进一步发展我国神经眼科学和更好地指导临床工作服务。方法:调查我院神经内科2009-06-01/2010-06-01全年有神经眼科表现的患者的临床资料,研究其疾病构成,神经眼科主要临床表现进行统计分析得出结论。结果:共调查神经内科住院患者651例,其中有神经眼科表现的为24.6%。有神经眼科表现的患者年龄为非正态分布,M=54岁;神经内科患者神经眼科症状最多的是复视44例,持续性视力下降42例,体征最多的是眼球运动障碍43例,眼球震颤38例。引起神经眼科表现的神经内科主要疾病构成:脑梗死49例、视神经脊髓炎17例、重症肌无力15例、脑出血14例、椎基底动脉供血不足12例、颅内静脉窦血栓形成5例、多发性硬化5例、炎性脱髓鞘病5例和颅内恶性肿瘤8例等,以上疾病占81.3%。有神经眼科表现的神经内科病变性质为循环障碍92例、非感染性炎症48例、恶性肿瘤8例、颅内感染性炎症4例、外伤3例、中毒2例、原因不明3例。结论:神经内科住院患者中24.6%有神经眼科表现。神经内科患者的神经眼科临床表现以复视、眼球运动障碍、持续性视力下降、眼球震颤最多。有神经眼科表现的神经内科主要疾病有脑梗死、NMO,MG、脑出血、椎基底动脉供血不足、CVST,MS、炎性脱髓鞘病和颅内恶性肿瘤。有神经眼科表现的神经内科疾病的病变性质主要为循环障碍和非感染性炎症。

Clinical study on neuro-ophthalmology features for neurology inpatients

AIM:To study the basic characteristics of hospitalized neurological patients in the aspects of neuro-ophthalmology,for the further development of neuro-ophthalmology and better clinical treatment.METHODS:Clinical data of patients who had neuro-ophthalmology symptoms or signs in neurology department of our hospital from June 1,2009 to June 1,2010 were collected,retrospective method was used to study the disease constitution and the main clinical manifestations,then statistical analysis was used to get the conclusion.RESULTS:Totally 160 patients who had neuro-ophthalmology disorders were selected from 651 patients,accounting for 24.6% of the total number of neurology hospitalizations in the same period.The age range of patients was 13-86 years old,with a median of 54 years old,and was abnormal distribution.The main clinical manifestations:44 patients with diplopia,43 patients with movement disorders,42 patients with sustained vision loss and 38 patients with nystagmus.Constitution of the main diseases:cerebral infarction in 49,neuromyelitis optica(NMO) in 17,myasthenia gravis(MG) in 15,cerebral hemorrhage in 14,vertebrobasilar insufficiency in 12,cranial venous sinus thrombosis(CVST) in 5,multiple sclerosis(MS) in 5,inflammatory demyelinating disease in 5 and malignant brain tumor in 8,which accounted for 81.3%.Pathological nature:92 patients were cerebral circulation disorders,48 patients were non-infectious inflammation,8 patients were malignant tumor,4 patients were intracranial infection inflammation,3 patients were trauma,2 patients were poisoning,and 3 patients were unknown reasons.CONCLUSION:Of the total neurology inpatients,24.6% had neuro-ophthalmogy manifestations.The most common clinical manifestations are diplopia,eye movement disorder,sustained vision loss and nystagmus.Neuro-ophthalmogy disease spectrum of neurology includes cerebral infarction,NMO,MG,cerebral hemorrhage,vertebrobasilar insufficiency,CVST,MS,inflammatory demyelinating disease and malignant brain tumor.The main pathological disorders are cerebral circulation and non-infectious inflammation.