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应用聚合酶链反应技术检测子宫颈组织中人乳头瘤病毒的研究
引用本文:王芝芬,刘丽.应用聚合酶链反应技术检测子宫颈组织中人乳头瘤病毒的研究[J].中华妇产科杂志,1994,29(2):103-105.
作者姓名:王芝芬  刘丽
作者单位:天津第二医学院附属第一中心医院,天津医学院
摘    要:应用聚合酶链反应(PCR)技术对53例正常宫颈组织、59例宫颈炎、12例宫颈癌、3例非典型增生及2例尖锐湿疣的子宫颈组织进行人乳头瘤病毒(HPV)-16,18的检测。结果:正常子宫颈组织中HPV-16,18的检出率低于宫颈癌组织,两者差异有显著意义;宫颈癌组织中HPV-16,18的检出率高于宫颈炎组织,两者差异无显著意义。提示:部分有HPV感染的宫颈炎可导致宫颈癌。

关 键 词:聚合酶链反应,子宫颈,乳头状瘤病毒

Detection of human papillomavirus in cervicaltissues using polymerase chain reaction
wangZhi-fen,Liu Li,Tang Hua,et al..Detection of human papillomavirus in cervicaltissues using polymerase chain reaction[J].Chinese Journal of Obstetrics and Gynecology,1994,29(2):103-105.
Authors:wangZhi-fen  Liu Li  Tang Hua  
Abstract:etection of human papillomavirus (HPV) 16and 18 infection by polymerase chain reaction (PCR)was carried out in patients with normal cervix 53cases, Chronic cervicitis with cervical erosion 59 cases,cervical cancer 12 cases, atypical hyperplasia 3 casesand condyioma acuminatum 2 cases. Results showedthat a significantly higher detective rate of HPV-16and 18 DNA in cervical cancer than in normal cervix,and a higher but not statistically significant positiverate than that in cervical erosion. It indicates thatsome cases of chronic cervicitis with HPV infectionmight develope into cervical carcinoma. This findingmay help in the early discovery and prevention ofcervical cancer.
Keywords:Polymerase chain reactionPapillomavirus Cervix  
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