| 妊娠期人乳头瘤病毒感染对母儿影响的探讨 |
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| 引用本文： | 郑晓霞,王谢桐,于珊.妊娠期人乳头瘤病毒感染对母儿影响的探讨[J].实用妇产科杂志,2011,27(3). |
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| 作者姓名： | 郑晓霞 王谢桐 于珊 |
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| 作者单位： | 1. 山东省济南市妇幼保健院,山东,济南,250001
2. 山东省立医院,山东,济南,250021 |
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| 摘 要： | 目的:探讨妇女妊娠期下生殖道人乳头瘤病毒(HPV)感染垂直传播及对婴儿的近期影响和母乳喂养与其传播的关系。方法:选择HPV感染的孕妇203例(研究组)和HPV阴性的正常孕妇(对照组)344例为研究对象,在分娩时取两组孕妇羊水、胎儿脐静脉血行HPV检测,做胎盘病理检查,并分析其母婴结局;同时对研究组新生儿的咽喉分泌物或外阴分泌物及产妇乳汁HPV进行检测,并随访产后半年和1年产妇乳汁HPV检测,及进行产后6月、12月、24月婴儿咽喉分泌物、外阴分泌物HPV检测。结果:①203例HPV阳性孕妇中,17例孕早、中期终止妊娠,余186例继续妊娠:阴道分娩89例(47.8%),剖宫产分娩97例(52.2%)。研究组胎膜早破、早产、胎儿生长受限、新生儿呼吸窘迫综合征、产后出血、产褥感染发生率与对照组相比,差异无统计学意义(P>0.05);②研究组分娩新生儿共186例,新生儿HPV感染128例,阳性率为68.8%。其中阴道分娩57例,剖宫产71例,两组比较差异无统计学意义(P>0.05);③研究组婴儿HPV转归:产后6个月婴儿HPV阳性率32.8%,产后12个月阳性率3.8%。产后两年复查,均转为阴性;④乳汁HPV检测:初乳...
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| 关 键 词： | 人乳头瘤病毒 妊娠 垂直传播 母乳喂养 |
Influence of Human Papillomavirus Infection during Pregnancy on Mothers and Children |
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| ZHENG Xiaoxia,WANG Xietong,YU Shan.Influence of Human Papillomavirus Infection during Pregnancy on Mothers and Children[J].Journal of Practical Obstetrics and Gynecology,2011,27(3). |
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| Authors: | ZHENG Xiaoxia WANG Xietong YU Shan |
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| Affiliation: | ZHENG Xiaoxia1,WANG Xietong2,YU Shan1(1.Jinan City Mother and Children Health Care Institution,Jinan Shandong 250001,China,2.Shandong Province Hospital,Jinan Shandong 250021,China) |
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| Abstract: | Objective:To study the vertical spread of HPV in pregnancy and its short term effect on infants,to clarify the relationship of breast milk feeding and HPV spread.Methods:203 HPV positive pregnant women(study group) and 344 HPV negative pregnant women(control group) were recruited in this study.The amniotic fluid and umbilical cord vein blood at delivary were collected for HPV test,also the placentas were sent for pathologic examination.Pharynx and vulva or pennis secretion of the newborns and 6,12,24 month ... |
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| Keywords: | HPV infection Pregnancy Vertical transmission Breast feeding |
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