数字化人体胸椎椎弓根一肋骨单元模型建立及生物力学研究

尽管胸椎椎弓根螺钉固定现在已广泛地应用于脊柱外科，但应用在中段胸椎（T4，T7）时的安全性已引起关注。椎弓根根外通道的解剖学研究表明椎弓根根外螺钉固定在生物力学稳定性方面非常重要。有限元分析法已广泛地应用于脊柱的复杂结构生物力学研究中。借助现代计算机技术和先进制造技术，术者可以通过三维有限元模型的建立、计算机辅助手术设计和预演等手段精确实施骨科手术，实现骨科手术的数字化、个性化和精确化，从而进一步提高手术安全性，改善临床效果。

Progress in the research on oxygen-induced apoptosis of alveolar epithelial cells and surfactant protein C,surfactant protein D in neonatal rats

Inhalation of high volume fraction oxygen for long time can result in hyperoxia lung injury, which is an important factor leading to the occurrence and development of neonatal bronchopuhnonary dysplasia. The pathogenesis is very complex in hyperoxia lung injury. Several recent studies have demonstrated that apoptosis is an important histological features during high-oxygen-induced lung injury, which plays a very important role in its pathogenesis. The hydrophilic surfactant protein D （SP-D） plays an important role in host defenseand innate immunity of the lung. It has increasing evident that SP involves in the pathogenesis of many pulmonary diseases.