| 沙棘油对二氧化硫所致小鼠肺氧化损伤的防护效应 |
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| 引用本文： | 武冬梅,孟紫强.沙棘油对二氧化硫所致小鼠肺氧化损伤的防护效应[J].劳动医学,2002,19(4):222-224. |
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| 作者姓名： | 武冬梅 孟紫强 |
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| 作者单位： | 山西大学环境医学与毒理学研究所，山西大学生命科学与技术学院，山西大学环境医学与毒理学研究所，山西大学生命科学与技术学院 太原030006，太原030006 |
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| 基金项目： | 国家自然科学基金资助 (编号 :30 0 70 647) |
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| 摘 要： | 目的 ]探讨抗氧化剂沙棘油对SO2 染毒小鼠肺组织中脂质过氧化物 (LPO)及抗氧化酶活性的影响。 方法 ]昆明小鼠随机分成对照组、SO2 吸入组及干预组 (沙棘油 4个剂量组 ) ,检测实验小鼠肺组织中LPO和谷胱甘肽硫转移酶 (GST)的活性。 结果 ]与SO2 吸入组相比 ,干预组小鼠肺组织中LPO含量减少 ,GST活性提高。 结论 ]抗氧化剂沙棘油对二氧化硫引起的肺氧化损伤有一定的拮抗作用
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| 关 键 词： | SO2 沙棘油 氧化损伤 脂质过氧化 |
| 文章编号： | 1006-3617(2002)04-0222-03 |
| 修稿时间： | 2002年1月18日 |
Protective Effects of Seabuckthorn Seed Oil on Oxidative Damage Induced by Sulphur Dioxide in Lung of Mice |
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| WU Dong mei,MENG Zi qing.Protective Effects of Seabuckthorn Seed Oil on Oxidative Damage Induced by Sulphur Dioxide in Lung of Mice[J].Journal of Labour Medicine,2002,19(4):222-224. |
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| Authors: | WU Dong mei MENG Zi qing |
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| Abstract: | This study is to investigate the effects of seabuckthorn seed oil on oxidative damage in lung of mice. The mice were randomly divided into three groups:a control group,SO 2 inhalation group and preventive group including 4 subgroups. The level of LPO and the activity of GST were determined. In preventive groups,the level of LPO was significantly decreased,and the activities of GST were significantly increased compared with these in SO 2 inhalation group. Conclusion] Seabuckthorn seed oil can prevent oxidative damage of lung induced by SO 2 in a certain degree. |
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| Keywords: | SO 2 seabuckthorn seed oil oxidative damage lipid peroxidation |
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