两种金黄色葡萄球菌产肠毒素差异的Meta分析

目的]分析耐甲氧西林金黄色葡萄球菌（ methicillin-resistant Staphylococcus aureus, MRSA ）和甲氧西林敏感金黄色葡萄球菌（ methieillin sensitive Staphylococcus aureus, MSSA ）之间产生肠毒素的差异，为评价MRSA、MSSA与金黄色葡萄球菌食物中毒之间的关系提供参考依据。方法]采用Meta分析方法对国内外1990-2008年发表的有关MRSA和MSSA产毒株率比较的文献进行汇总、归纳和统计分析。结果]共检索到7篇文献，合并总RR值为2．18，95％可信区间为1．58～2．99。MRSA中的产毒株率是MSSA的2．18倍。结论]MRSA产生肠毒素的概率远大于MSSA。

Comparative Prevalence of the Enterotoxin-producing Isolates in Two Strains of Saphylococcus Aureus Using Meta-analysis

Objective ] To analysis the difference in enterotoxin production between methicillin-resistant Staphylococcus aureus（ MRSA ）and methicillin sensitive Staphylococcus aureus（ MSSA ）so as to provide a reference to evaluate their association with staphylococcus aureus food poisoning. Methods ] Meta-analysis was used to evaluate the data extracted from published articles domestic and abroad relevant to comparative prevalence of the enterotoxin-producing isolates in MRSA and MSSA during 1992-2008. Results ] A total of 7 articles were retrieved. The overall effect indicator RR （ 95%CI ）was 2.18 （ 1.58-2.99 ）. The prevalence of the enterotoxin-producing isolates in MRSA was 2.18 fold greater than in MSSA. Conclusion ] The probability of enterotoxin production in MRSA was far more than in MSSA.