肿瘤标志物在子宫内膜癌诊断和预后评估中的研究进展

子宫内膜癌(EC)为女性生殖道常见的3大恶性肿瘤之一，近年其发病率在世界范围内呈上升趋势，成为严重威胁妇女健康和生命的主要肿瘤之一。EC早期临床症状隐匿，因此目前急需寻找特异度和敏感度高的肿瘤标志物，用于EC的早期诊断和预后评估，以进一步提高患者生存率。随着肿瘤生物学与免疫学的发展，目前发现多种肿瘤标志物可用于EC的诊断和预后评估。笔者拟就近期所研究的肿瘤标志物进行综述，旨在为EC的诊断与进一步研究提供理论参考。

Research progress of tumor markers on diagnosis and prognosis assessment of endometrial carcinoma

Endometrial carcinoma(EC) is one of the three common malignant neoplasms in females′ genital tract.The morbidity of EC is rising recently in the world, and the EC has become the major one of the tumors which threaten the health and life of women. The early clinical symptoms of EC is hidden, so it is necessary to seek for the tumor markers which have the higher specificity and sensitivity in the early diagnosis and prognosis assessment of EC to improve the survival rate of patients. At present, with the developments of biology and immunology, more and more tumor markers has been discovered.This review mainly concludes the newly researchful markers to provide the theory basis about the diagnosis, prognosis assessment and further study of EC.