室内颗粒物污染对儿童哮喘影响的病例对照研究

目的探讨室内大气颗粒物对儿童哮喘的影响。方法于2012—2013年采用病例-对照研究方法,对武汉市82名儿童居室内环境污染情况等进行问卷调查,对室内颗粒物浓度进行检测。结果病例组儿童室内PM_(10)平均浓度高于对照组(P0.05)。将两种颗粒物质量浓度划分为0μg/m~3~、100μg/m~3~、150μg/m~3~、200μg/m~3~不同等级,以0μg/m~3~为参照组,随着污染物浓度的升高,儿童哮喘发生的OR值逐渐升高;在调整混杂因素后,其OR值仍呈增加趋势,尤其是PM_(10)浓度在200μg/m~3以上时,调整后OR值为27.05(95%CI:1.52~482.94)。结论室内PM_(2.5)和PM_(10)对儿童哮喘有影响,且存在剂量-反应关系。

Impact of indoor particulate matters pollution on childhood asthma: a case-control study

Objective To understand the effects of indoor particulate matters on childhood asthma.Methods With case-control study,82 children in urban of Wuhan were interviewed at home,and the particulate matter concentrations in children'living room were measured.Results Compared with the control group,the concentrations of PM10 in living rooms were significantly higher among the children with asthma (P＜0.05) with a dose-dependent manner.Adjusted by the covariates,PM10 significantly increased the risk of asthma,especially when the concentration exceeded 200 μg/m3 (OR=27.05,95％CI:1.52-482.94).Conclusion PM10 and PM2.5 in indoor air may increase childhood asthma,especially when it is in the higher level.