有机氟作业工人尿氟检测结果分析

目的了解有机氟作业工人尿氟含量水平。方法采集某企业7个车间接触有机氟（二氟一氯甲烷、三氟氯乙烯、四氯乙烯、八氟异丁烯）工人656名，以及该企业从未接触过有机氟作业的电工、管理、后勤人员255名的晨尿，按WS／T30-1996，吸取10．0ml尿液于50ml塑料烧杯中，加入总离子强度缓冲液10．0ml，用PXJ-IC^＋型离子活度计，氟离子选择电极法测定。用t检验、F检验和百分位数程序对数据进行统计学处理分析。结果656名有机氟作业工人尿氟含量为0．10～4．74mg／L，均值1．08mg／L，255名对照组工人尿氟含量为0．16～2．95mg／L，均值0．90mg／L，作业组尿氟含量均值明显高于对照组，差异有统计学意义（P〈0．01）。对照组尿氟含量呈偏态分布，尿氟百分位数（P2.5～P97.5）为0．23～2．27mg／L，建议本地区尿氟正常值上限为2．3mg／L。作业组男性尿氟均值水平高于女性（P〈0．01）；作业组尿氟含量与年龄、接触工龄差异无统计学意义，F=2．32，P〉0．05，但有随工龄增长，尿氟均值增加的趋势。结论有机氟作业组与对照组的尿氟含量有显著差别，作业组工人尿氟含量与性别有关，与年龄无关，与接触工龄关系不显著；本地区尿氟正常值上限为2．3mg／L。

Urinary Fluoride of Workers Exposed to Organic Fluorine

Objective To find out the urine fluoride concentration levels in workers exposed to organic fluorine. Methods The urinary fluoride was detected by PXJ-IC^＋ ion-meter and fluoride ion by electrode methed. Results The urine fluoride concentrations in control group showed skew distribution. The percentile of urinary fluoride concentrations （P2.5 - P97. 5 ） in control group was 0. 23 to 2.27 mg/L. The mean urine fluoride concentration of 656 workers exposed to fluorine （ 1.08 mg/L） was significantly higher than those of the control （0. 90 mg/L） （P 〈0. 01 ）. The mean urine fluoride concentration of male was higher than that of female（P 〈 0. 01 ）. There was no significant relationship between urine fluoride concentrations and age or length of service, but it seemed that the urine fluoride concentrations figured on a rising trend along with the increase in length of service. Conclusion There were significant differences in the urine fluoride concentration between workers exposed to organic fluorine and the control. There was correlation between the urine fluoride concentration of workers exposed to organic fluorine in sexes, but no significant correlation in age and length of service. The authors suggested that the upper limit of normal range for urine fluoride concentration was 2. 3 mg/L.