| 氩氦刀冷冻治疗原发性肝癌的初步临床研究 |
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| 引用本文： | 周霖,杨永平,冯永毅,陆荫英,王春平,王新真,安林静,张昕,王福生.氩氦刀冷冻治疗原发性肝癌的初步临床研究[J].癌症,2009,28(1):58-62. |
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| 作者姓名： | 周霖 杨永平 冯永毅 陆荫英 王春平 王新真 安林静 张昕 王福生 |
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| 作者单位： | 周霖,Lin Zhou(军医进修学院,北京,100853;解放军第302医院肝癌治疗研究中心,北京,100039);杨永平,冯永毅,陆荫英,王春平,王新真,安林静,张昕,王福生,Yong-Ping Yang,Yong-Yi Feng,Yin-Ying Lu,Chun-Ping Wang,Xin-Zhen Wang,Lin-Jing An,Xin Zhang,Fu-Sheng Wang(解放军第302医院肝癌治疗研究中心北京,100039)
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| 摘 要： | 背景与目的：近年来氩氦刀冷冻治疗肝癌发展迅速，本研究旨在通过回顾性分析，评价氩氦刀冷冻治疗无法手术切除的原发性肝癌的临床疗效。方法：选择124例经氩氦刀冷冻治疗的原发性肝癌患者．根据巴塞罗那分期分成早期、中期及进展期肝癌组，以治疗后患者的临床表现、局部病灶CT变化、AFP下降情况、术后并发症的发生及平均生存时间作为评价指标。结果：氩氦刀冷冻治疗肝癌后患者的并发症少，82．6％的患者术后AFP降低，92．3％的肿瘤缩小或保持不变。截止至2008年4月．仍有14例患者生存．110例患者死亡。早期、中期及进展期肝癌组的中位生存时间分别为31．25个月、17．41个月、6．82个月。结论：对于无法切除的中晚期肝癌，氩氦刀治疗的并发症少．有一定的疗效。
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| 关 键 词： | 原发性肝癌 冷冻治疗 疗效 并发症 生存期 |
Efficacy of argon-helium cryosurgical ablation on primary hepatocellular carcinoma: a pilot clinical study |
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| Lin Zhou, Yong-Ping Yang, Yong-Yi Feng, Yin-Ying Lu, Chun-Ping Wang, Xin-Zhen Wang, Lin-Jing An, Xin Zhang , Fu-Sheng Wang. PLA Postgraduate Medical School,Beijing,P. R. China . Liver Carcinoma Therapy Research Center PLA Hospital,P. R. China.Efficacy of argon-helium cryosurgical ablation on primary hepatocellular carcinoma: a pilot clinical study[J].Chinese Journal of Cancer,2009,28(1):58-62. |
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| Authors: | Lin Zhou Yong-Ping Yang Yong-Yi Feng Yin-Ying Lu Chun-Ping Wang Xin-Zhen Wang Lin-Jing An Xin Zhang Fu-Sheng Wang PLA Postgraduate Medical School Beijing P R China Liver Carcinoma Therapy Research Center PLA Hospital P R China |
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| Affiliation: | Lin Zhou,1,2 Yong-Ping Yang,2 Yong-Yi Feng,2 Yin-Ying Lu,2 Chun-Ping Wang,2 Xin-Zhen Wang,2 Lin-Jing An,2 Xin Zhang2 , Fu-Sheng Wang21. PLA Postgraduate Medical School,Beijing,100853,P. R. China 2. Liver Carcinoma Therapy Research Center PLA 302 Hospital,100039,P. R. China |
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| Abstract: | Background and Objective: Recent years, great progression has been made in treating primary hepatocellular carcinoma (HCC) with argon- helium cryosurgical ablation. This study was to evaluate its efficacy on unresectable primary HCC. Methods: A total of 124 primary HCC patients were divided into early stage, middle stage and advanced stage groups according to BCLC staging classification. Clinical symptoms, tumor size, serum level of alpha-fetoprotein (AFP), complications, and survival time were analyzed. Re... |
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| Keywords: | liver neoplasm cryosurgery efficacy complication survival |
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