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胃癌组织PAKl表达及其与临床病理特征和生存的关系(英文)
引用本文:王娟霞,周永宁,邹绍静.胃癌组织PAKl表达及其与临床病理特征和生存的关系(英文)[J].癌症,2010(7).
作者姓名:王娟霞  周永宁  邹绍静
作者单位:Department of Hepatopathy;the Second Hospital;Lanzhou University;Department of Gastroenterology;the First Hospital;
基金项目:National Natural Science Foundation of China (No. 30872478)
摘    要:Background and Objective:Recent studies proved that P21-activated kinase 1(PAK1) is highly expressed in many kinds of tumor and plays an important role in genesis,development,and metastasis of tumor.We aimed to detect the expression of PAK1 in gastric carcinoma and to analyze its relationship with clinicopathological features and prognosis of gastric carcinoma.Met hods:Tissue microarray and immunohistochemical staining were performed to detect PAK1 in paraffin specimens of 189 gastric carcinomas,54 paracanc...

关 键 词:表达  生存  临床病理特征  胃癌组织  

Correlations of P21-activated kinase 1 expression to clinicopathological features of gastric carcinoma and patients' prognosis
Juan-Xia Wang,Yong-Ning Zhou,Shao-Jing Zou,Tao-Wen Ren,Zhi-Yi Zhang.Correlations of P21-activated kinase 1 expression to clinicopathological features of gastric carcinoma and patients' prognosis[J].Chinese Journal of Cancer,2010(7).
Authors:Juan-Xia Wang  Yong-Ning Zhou  Shao-Jing Zou  Tao-Wen Ren  Zhi-Yi Zhang
Affiliation:Juan-Xia Wang1,Yong-Ning Zhou2,Shao-Jing Zou2,Tao-Wen Ren2,Zhi-Yi Zhang3 1 Department of Hepatopathy,the Second Hospital,Lanzhou University,Lanzhou,Gansu 730030,P.R.China,2 Department of Gastroenterology,the First Hospital,Gansu 730000,3 Wuwei Tumour Hospital,Wuwei,Gansu 733000
Abstract:Background and Objective:Recent studies proved that P21-activated kinase 1(PAK1) is highly expressed in many kinds of tumor and plays an important role in genesis,development,and metastasis of tumor.We aimed to detect the expression of PAK1 in gastric carcinoma and to analyze its relationship with clinicopathological features and prognosis of gastric carcinoma.Methods:Tissue microarray and immunohistochemical staining were performed to detect PAK1 in paraffin specimens of 189 gastric carcinomas,54 paracance...
Keywords:Gastric neoplasm  PAK1  immunohistochemistry  clinicopathological feature  survival  
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