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| 激活转录因子3的过表达对食管癌细胞生长的抑制作用 | |
| 引用本文： | 谢仰民,谢剑君,周飞,侯健,曹君君,许丽艳,李恩民.激活转录因子3的过表达对食管癌细胞生长的抑制作用[J].癌变．畸变．突变,2009,21(4):258-262,267. |
| 作者姓名： | 谢仰民 谢剑君 周飞 侯健 曹君君 许丽艳 李恩民 |
| 作者单位： | 1. 汕头大学医学院实验动物中心,广东,汕头,515041 2. 汕头大学医学院实验动物中心,广东,汕头,515041;汕头大学医学院生物化学与分子生物学教研室,广东,汕头,515041 3. 汕头大学医学院生物化学与分子生物学教研室,广东,汕头,515041 4. 汕头大学医学院,肿瘤病理研究室,广东,汕头,515041 |
| 基金项目： | 广东省科技厅计划项目 |
| 摘 要： | |
| 关 键 词： | 食管癌 激活转录因子3 细胞生长 |
Over-expression of ATF3 Inhibits the Proliferation of Esophageal Squamous Carcinoma Cells |
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| XIE Yang-min,XIE Jian-jun,ZHOU Fei,HOU Jian,CAO Jun-jun,XU Li-yan,LI En-min.Over-expression of ATF3 Inhibits the Proliferation of Esophageal Squamous Carcinoma Cells[J].Carcinogenesis,Teratogenesis and Mutagenesis,2009,21(4):258-262,267. | |
| Authors: | XIE Yang-min XIE Jian-jun ZHOU Fei HOU Jian CAO Jun-jun XU Li-yan LI En-min |
| Affiliation: | XIE Yang-min1,XIE Jian-jun2,ZHOU Fei1,2,HOU Jian2,CAO Jun-jun1,XU Li-yan3,LI En-min2,(1.Department of Experimental Animal Center,Medical College of Shantou University,Shantou 515041,2.Department of Biochemistry , Molecular Biology,3.Department of Pathology,The Key Immunopathology Laboratory of Guangdong Province,China) |
| Abstract: | BACKGROUND AND AIM: ATF3 was down-regulated in esophageal squamous cell carcinoma(ESCC),but the roles of ATF3 in ESCC cells still remained unclear.The purpose of this study was to explore the effect of ATF3 on the proliferation of ESCC cells.MATERIALS AND METHODS: The recombinant expressing plasmid was constructed by inserting the full coding sequence of ATF3 gene into the eukaryotic expressing vector pcDNA3.Then,the expressing plasmid was stably transfected into EC109 cells,an ESCC cell line,and the over-e... |
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