| 盐酸格拉司琼预防肝癌患者介入治疗后恶心呕吐的疗效观察 |
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| 引用本文： | 寇光.盐酸格拉司琼预防肝癌患者介入治疗后恶心呕吐的疗效观察[J].实用癌症杂志,2006,21(1):79-80. |
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| 作者姓名： | 寇光 |
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| 作者单位： | 330006,江西省人民医院药剂科 |
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| 摘 要： | 目的探讨盐酸格拉司琼对预防肝癌患者介入治疗后引起的恶心、呕吐的疗效。方法将60例行介入治疗的患者随机分为格拉司琼治疗组（治疗组）和胃复安＋安定对照组（对照组）。治疗组在介入治疗术中未灌注化疗药物前，通过导管向动脉内注射盐酸格拉司琼。对照组在介入治疗术前30min肌注胃复安和安定。观察2组患者术后的恶心、呕吐等不良反应。结果盐酸格拉司琼组的止吐疗效明显高于对照组，2组比较有显著性差异（P〈0．05）；治疗组其他不良反应发生次数明显少于对照组。结论盐酸格拉司琼对介入化疗栓塞术患者是有效的止吐药物，值得临床推广应用。
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| 关 键 词： | 盐酸格拉司琼 肝肿瘤 介入治疗 呕吐 预防 |
| 文章编号： | 1001-5930（2006）01-0079-02 |
| 收稿时间： | 2005-11-15 |
| 修稿时间： | 2005-11-152005-12-27 |
Effect of Granisetron on Vomitting Caused by Transarterial Chemoembolization (TACE) |
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| KOU Guang.Effect of Granisetron on Vomitting Caused by Transarterial Chemoembolization (TACE)[J].The Practical Journal of Cancer,2006,21(1):79-80. |
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| Authors: | KOU Guang |
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| Abstract: | Objective To evaluate the prophylactic efficacy of granisetron on vomiting caused by TACE.Methods 60 Patients were randomly divided into two groups to receive either granisetron via liver artery injection(n=30) or metoclopramidum combined with diazepam as controls(n=30).The antiemetic efficacy were compared between the two groups for 5 consecutive days after TACE.Results The effective rate of granisetron group was significantly higher than that of the control group(P<0.05).Conclusion Granisetron is an effective antiemetic drug in controlling vomiting caused by TACE and should be advocated in clinical practice. |
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| Keywords: | Granisetron Liver neoplasms Transarterial chemoembolization(TACE) Vomit Prevent |
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