| 局部进展期胃癌术后调强放疗的剂量学研究 |
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| 引用本文： | 邓清华,李浦,闫风琴,刘鹏,卢珂,汤忠祝,马胜林,朱远.局部进展期胃癌术后调强放疗的剂量学研究[J].中华肿瘤防治杂志,2011,18(9):713-715. |
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| 作者姓名： | 邓清华 李浦 闫风琴 刘鹏 卢珂 汤忠祝 马胜林 朱远 |
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| 作者单位： | 浙江省肿瘤医院腹部放射治疗科,浙江杭州,310022 |
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| 摘 要： | 目的:通过比较局部进展期胃癌术后调强放疗(IMRT)与三维适形放疗(3D-CRT)计划,评价IMRT与3D-CRT靶区与危及器官剂量分布的优劣。方法:对29例D2手术后完全切除的局部进展期胃癌病例同时作IMRT和3D-CRT计划,处方剂量45 Gy,依据DVH和等剂量曲线评价上述两种治疗计划。结果:与3D-CRT相比,IMRT靶区剂量适形性更好,平均剂量更高(均为P<0.001);IMRT靶区剂量均匀性亦更好(P<0.05)。肝脏平均剂量V5、V20均明显降低(分别为P<0.001及P<0.05);左肾平均剂量、V12、V22.5亦显著减低(均为P<0.001);而右肾平均剂量、V12、V22.5及脊髓最高剂量两者相比差异均无统计学意义。结论:局部进展期胃癌术后患者,IMRT比3D-CRT靶区剂量分布更好,同时能使肝脏和左肾得到更好的保护。
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| 关 键 词： | 放射疗法 适形 胃肿瘤/放射疗法 放射治疗剂量 |
Comparison of desimetric parameters between IMRT and 3D-CRT for postoperative irradiation in locally advanced gastric carcinoma |
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| DENG Qing-hua,LI Pu,YAN Feng-qin,LIU Peng,LU Ke,TANG Zhong-zhu,MA Sheng-lin,ZHU Yuan.Comparison of desimetric parameters between IMRT and 3D-CRT for postoperative irradiation in locally advanced gastric carcinoma[J].Chinese Journal of Cancer Prevention and Treatment,2011,18(9):713-715. |
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| Authors: | DENG Qing-hua LI Pu YAN Feng-qin LIU Peng LU Ke TANG Zhong-zhu MA Sheng-lin ZHU Yuan |
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| Affiliation: | DENG Qing-hua,LI Pu,YAN Feng-qin,LIU Peng,LU Ke,TANG Zhong-zhu,MA Sheng-lin,ZHU Yuan Department of Stomach Radiation Oncology,Zhejiang Cancer Hospital,Hangzhou 310022,P.R.China |
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| Abstract: | OBJECTIVE: To compare the radiotherapy plan between intensity modulated radiation therapy(IMRT) and 3-dimensional conformal radiation therapy(3D-CRT),and evaluate the dose distribution in target volume and organs at risk.METHODS:Twenty-nine patients with locally advanced gastric carcinoma were included in this study.For each patient IMRT plan and 3D-CRT plan were generated.The dose reference point was at isocenter and prescribed to 45 Gy.Dose volume histogram(DVH) and dose distribution curves were used to e... |
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| Keywords: | radiotherapy comformal stomach neoplasms/radiotherapy radiotherapy dosage |
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