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食管癌研究关键科学问题的认识和思考CSCD
引用本文:王立东,韩文莉,宋昕,赵学科,胡守佳,王盼盼,杨苗苗.食管癌研究关键科学问题的认识和思考CSCD[J].肿瘤防治研究,2020,47(2):83-89.
作者姓名:王立东  韩文莉  宋昕  赵学科  胡守佳  王盼盼  杨苗苗
作者单位:450052 郑州,郑州大学第一附属医院,郑州大学基础医学院,省部共建食管癌防治国家重点实验室
基金项目:科技部国家重点研发计划“精准医学研究”重点专项(2016YFC0901403);国家自然科学基金(81872032,U1804262);河南省自然科学基金(162300410238)。
摘    要:河南医疗队从1959年11月进驻河南林县(现林州市)开展食管癌高发现场防治研究至今已60年。60年来,河南三代医学专家前仆后继,坚持林县食管癌高发现场防治和实验室研究相结合,在食管癌发生分子机制和早期发现、癌前病变干预和防治方法等方面取得了一系列举世瞩目的科研成果,造福万千患者。本文基于笔者课题组34年食管癌防治研究实践,重点阐述对中国食管癌流行特征、关键科学问题和重要研究方向等的理解和思考,为食管癌防治研究同道提供参考。

关 键 词:食管癌  病因与干预  高危人群分子分型  早期发现  智能医学
收稿时间:2019-07-24

Understanding and Thinking About Key Scientific Issues in Esophageal Cancer Research
WANG Lidong,HAN Wenli,SONG Xin,ZHAO Xueke,HU Shoujia,WANG Panpan,YANG Miaomiao.Understanding and Thinking About Key Scientific Issues in Esophageal Cancer Research[J].Cancer Research on Prevention and Treatment,2020,47(2):83-89.
Authors:WANG Lidong  HAN Wenli  SONG Xin  ZHAO Xueke  HU Shoujia  WANG Panpan  YANG Miaomiao
Affiliation:State Key Laboratory of Esophageal Cancer Prevention and Treatment and He’nan Key Laboratory for Esophageal Cancer Research of The First Af filiated Hospital of Zhengzhou University, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450052, China
Abstract:He’nan Medical Team has stationed in Lin county(now Linzhou City)of He'nan Province for 60 years since November 1959 to carry out prevention and treatment research on high incidence of esophageal cancer.In the past 60 years,three generations of medical experts in He’nan Province have made a series of remarkable scientific research achievements in the molecular mechanism and early detection of esophageal cancer,intervention and prevention methods of precancerous lesions,and benefited thousands of patients.Based on the 34-year research of esophageal cancer prevention and treatment in our research group,this paper focuses on the understanding and thinking about the epidemic characteristics,key scientific issues and important research directions of esophageal cancer in China,so as to provide a reference for the prevention and treatment of esophageal cancer.
Keywords:Esophageal cancer  Etiology and intervention  Molecular typing of high risk population  Early detection  Intelligent medicine
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