Psychometric properties of the simplified Chinese version of the EORTC QLQ-BR53 for measuring quality of life for breast cancer patients |
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Authors: | Chonghua Wan Xueliang Tang Xin M Tu Changyong Feng Susan Messing Qiong Meng Xiaoqing Zhang |
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Affiliation: | (1) Faculty of Public Health, Kunming Medical College, Kunming, 650031, Yunnan, China;(2) Oncological Hospital of Yunnan Province, Kunming, 650031, China;(3) Department of Biostatistics and Computational Biology, University of Rochester, 601 Elmwood Ave., Box 630, Rochester, NY 14642, USA |
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Abstract: | A Simplified Chinese version of the EORTC QLQ-BR53 was evaluated using responses from 233 patients with breast cancer in China
by assessing the construct and criterion-related validity, internal consistency and test–retest reliability, and responsiveness
as measured by score changes of the scales. Internal consistency reliability measured by Cronbach’s coefficient α is greater than 0.75 for most multi-item scales except cognitive functioning (0.41) and breast symptoms (0.71). Test–retest
reliability coefficients for all domains are greater than 0.80 with the exception of physical functioning (0.65), social functioning
(0.75), appetite loss (0.75), diarrhea (0.72), and body image (0.72). Correlation and factor analysis among domains and items
showed good construct validity for both QLQ-C30 and QLQ-BR23. Score changes over time were observed in most domains except
emotional functioning, global health status/QOL, dyspnoea, constipation, diarrhea, financial difficulties, sexual functioning,
sexual enjoyment, and breast symptoms. Therefore, the Simplified Chinese version of QLQ-BR53 shows reasonable validity, reliability,
and responsiveness and can be used to measure QOL for Chinese patients with breast cancer. |
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Keywords: | Breast cancer QLQ-C30 and QLQ-BR23 Quality of life Psychometric properties |
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