| AN IMMUNOHISTOCHEMICAL STUDY OF NEUROENDOCRINE CELLS IN COLONIC CARCINOMA |
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| 作者姓名： | 虞积耀 李燕东 王嘉玲 |
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| 作者单位： | General Hospital of The Navy，Beijing 100037 Beijing Fuxing Hospital |
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| 摘 要： | ＡＮＩＭＭＵＮＯＨＩＳＴＯＣＨＥＭＩＣＡＬＳＴＵＤＹＯＦＮＥＵＲＯＥＮＤＯＣＲＩＮＥＣＥＬＬＳＩＮＣＯＬＯＮＩＣＣＡＲＣＩＮＯＭＡＹｕＪｉｙａｏ；虞积耀Ｌｉｙａｎｄｏｎｇ；李燕东ＷａｎｇＪｉａｌｉｎｇ；王嘉玲（１ＧｅｎｅｒａｌＨｏｓｐｉｔａｌｏｆＴｈ...
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| 修稿时间： | 12 February 1996 |
An immunohistochemical study of neuroen-docrine cells in colonic carcinoma |
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| Yu Jiyao,Li Yandong,Wang Jialing.AN IMMUNOHISTOCHEMICAL STUDY OF NEUROENDOCRINE CELLS IN COLONIC CARCINOMA[J].Chinese Journal of Cancer Research,1996,8(2):105-108. |
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| Authors: | Yu Jiyao Li Yandong Wang Jialing |
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| Affiliation: | (1) General Hospital of the Navy, 100037 Beijing;(2) Beijing Fuxing Hospital, 100037 Beijing |
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| Abstract: | Seventy-four cases of colonic cancer were studied by immunohistochemistry using anti-Chromogranin A,gastrin, somatostatin, serotonin, glucogon and human chorionic gonadotropin (HCG) to observe the neuroendocrine cell in colonic cancer. It was found that 27of 74 colonic carcinoma showed variable extent of CgA staining (36.5%). Glucagon and HCG was differently the most frequent in hormone antigens in colonic cancer and in metastatic lymph nodes. The endocrine positive colonic carcinomas are more frequent in poorly-differentiated than in well-differentiated (P<0.05). It suggests that there were different NE cells Producing different hormones in colonic cancer. Different hormones may act on different types of colonic cancer. |
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| Keywords: | Neuroendocrine cell Colonic cancer Immunohistochemistry |
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