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Contribution of diffusion‐weighted imaging to dynamic contrast‐enhanced MRI in the characterization of papillary breast lesions
Authors:Seyma Yildiz MD  Huseyin Toprak MD  Yeliz Emine Ersoy MD  Fatma Ümit Malya MD  Ayşe Ahsen Bakan MD  Ayşe Aralaşmak MD  Zuhal Gucin MD
Affiliation:Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey
Abstract:Papillary lesions have a broad spectrum of appearances on magnetic resonance imaging (MRI ). The purpose of this study was to evaluate whether apparent diffusion coefficient (ADC ) values of papillary lesions can be used to characterize lesion as benign or malignant. This retrospective study included 29 papillary lesions. Diagnostic values of dynamic contrast‐enhanced MRI (DCE‐MRI), DWI ‐ADC , and DCE ‐MRI plus DWI ‐ADC were separately calculated. The malignant papillary lesions (0.744×10?3 mm2/s) exhibited significantly lower mean ADC values than the benign lesions (1.339×10?3 mm2/s). Addition of DWI to standard DCE ‐MRI provided 100% sensitivity. We hypothesized that this combination may prevent unnecessary excisional biopsies.
Keywords:breast DWI  breast MRI  breast papillary lesion
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