盐酸米诺环素复合明胶海绵治疗干槽症的临床研究

目的:比较盐酸米诺环素复合明胶海绵与碘仿纱条治疗干槽症的疗效。方法:58例确诊为干槽症的患者经常规清创后,随机均分为2组。实验组牙槽窝内置入盐酸米诺环素复合明胶海绵;对照组填塞碘仿纱条,随访比较其疗效。结果:组间比较实验组/对照组:优(例)23/16;良(例)6/11;可(例)0/2],Kruskal-Wallis检验法检验,疗效评价等级为"优"的实验组病例数多于对照组(P<0.05)。结论:盐酸米诺环素复合明胶海绵对干槽症的疗效优于碘仿纱条。

Minocycline Hydrochloride Ointment/Absorbable Gelatin Sponge in the Treatment of Dry Socket

Objective： The purpose of this study was to compare the effects between minocycline hydrochloride ointment/ absorbable gelatin sponge and iodoform gauze on the treatment of dry socket. Methods： 58 patients with dry socket were randomly allocated into two groups, 29 patients in experiment group were treated with minocycline hydrochloride ointment/ absorbable gelatin sponge in the tooth socket after debridement, the control group were placed with iodoform gauze. Results： Curative effect of experimental group / control group were excellent （cases） 23/16; good （cases） 6 / 11 cases; may （cases） 0 / 2. The results of Kruskal-Wallis test was P〈0.05, there were significant difference in the case number between two groups at curative effect of excellent. The proportion of the evaluation level was better in the experiment group. Conclusion： The minocycline hydrochloride ointment/absorbable gelatin sponge seems to be better in the treatment of dry socket.