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| 多西环素缓释凝胶治疗牙周炎的临床研究 | |
| 引用本文： | 金鸿莱,胡纯贞,陈建国,肖忠革,孙达华.多西环素缓释凝胶治疗牙周炎的临床研究[J].上海口腔医学,2003,12(4):250-252. |
| 作者姓名： | 金鸿莱 胡纯贞 陈建国 肖忠革 孙达华 |
| 作者单位： | 1. 上海第二医科大学,附属第九人民医院,口腔医学院,口腔内科,上海,200011 2. 江苏镇江市口腔医院,口腔内科,江苏,镇江,212000 3. 上海第二医科大学,附属第九人民医院,口腔医学院,临床药学室,上海,200011 |
| 摘 要： | 目的观察多西环素缓释凝胶剂治疗牙周炎的临床疗效。方法选取牙周炎患者30例,采用自身对照法,随机分为2组,试验组与对照组各30例,试验组治疗药物为多西环素凝胶,对照组为台氏液。观察用药前后临床症状及各项牙周指数PLI、GI、SBI、PD、AL、MD的变化。结果试验组牙周炎患者用药4周,停药1周时PLI、GI、SBI、PD、AL与用药前相比均有非常显著性差异(P<0.01);试验组与对照组疗效比较,两者有非常显著差异(P<0.01)。治疗过程中均未发现药物不良反应。结论多西环素凝胶是一种局部治疗牙周炎的安全有效的药物。 |
| 关 键 词： | 多西环素缓释凝胶 台氏液 牙周炎 药物治疗 |
| 文章编号： | 1006-7248(2003)04-0250-03 |
| 修稿时间： | 2002年11月18 |
A Clinical Study of Doxycycline Slow-Release Gel on Periodontitis Chemotherapy |
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| JIN Hong-lai ,HU Chun-zheng ,CHEN Jian-guo ,Xiao Zhong-ge ,Sun Da-hua ..A Clinical Study of Doxycycline Slow-Release Gel on Periodontitis Chemotherapy[J].Shanghai Journal of Stomatology,2003,12(4):250-252. | |
| Authors: | JIN Hong-lai HU Chun-zheng CHEN Jian-guo Xiao Zhong-ge Sun Da-hua |
| Affiliation: | Department of Periodontics, Ninth People's Hospital, School of Stomatology, Shanghai Second Medical University, Shanghai 20001, China. |
| Abstract: | Objective To observe the ef fe ct of Doxycycline slow-release on periodontitis therapy.Methods30patients with c hronic periodontitis were chosen and devided into2groups randomly,these cases we re given Doxycycline slow-re-lease and Zinciodati Comp solution.PLI,GI,SBI,P D,AL,MD and clinical syptoms were observed before and after taking drug.Result s The indose of PLI,GI,SBI,PD,AL,MD were decreased significantly after the use of Doxycycline slow-re-lease gel(P<0.05),the effects of the Doxycycline was better than Zinciodati Comp solution(P<0.01),no adverse drug side effects were found during trial.Conclusion The use of Doxycycline slow-release gel is one of the safe and effective chemotherapy on periodontitis. |
| Keywords: | Doxycycline Slow-Release Gel Zinciodati Comp solution Periodontitis |
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