超声龈下刮治同步药物冲洗对牙周炎的治疗作用

目的探讨超声龈下刮治同步药物冲洗对牙周炎的治疗效果。方法选取中、重度慢性牙周炎患牙34颗,随机分为三组：A组（蒸馏水组）超声龈下刮治同步无菌蒸馏水冲洗（11颗牙）;B组（消炎痛组）超声龈下刮治同步0.1%消炎痛药物冲洗（13颗牙）;C组（甲硝唑组）超声龈下刮治同步0.2%甲硝唑药物冲洗（10颗牙）。比较龈上洁治、龈下刮治前后28日临床检查指标,及治疗后7、28日龈沟液的量和龈沟液中IL-6的水平变化。结果三组治疗后菌斑指数（PLI）、探诊深度（PD）、龈沟出血指数（SB I）、龈沟液的量及龈沟液中IL-6水平明显降低,有显著性差异;附着丧失（AL）降低不明显;消炎痛组和甲硝唑组治疗后龈沟液中IL-6水平降低程度大于蒸馏水组,有显著性差异。结论超声龈下刮治同步药物冲洗能够明显提高牙周炎的治疗效果。

Effect of ultrasonic scaling combining with simultaneous agents irrigation in treatment of periodontitis

Objective To investigate the clinical effect of periodontal desease by ultrasonic scaling combining with simultaneous agents irrigation.Methods Thirty-four teeth with moderate or advanced chronic periodontal disease were divided into three groups at random,A） Control group：ultrasonic scaling combining with distilled water（11 teeth）;B） group indomethacin（IND）： ultrasonic scaling combining with 0.1% of indomethacin（13 teeth）;C） group metronidazole（MTZ）： ultrasonic scaling combining with 0.2% of metronidazole（10 teeth） irrigation.The data of clinical indexes were recorded before therapy and at the 28 th day after therapy.The volumn of gingival crevicular fluid（GCF） and the level of interleukin-6（IL-6） was detected before therapy and at the 7 th and 28 th day after therapy.Results A significant decrease was shown in plaque index,probing depth,sulcus bleeding index,the volumn of GCF and the level of IL-6 of the three groups compared with baseline（P0.05）.Though there was some decrease at attachment level,there was no statistically significant difference.The decrease of the level of IL-6 of group IND and group MTZ was significantly higher than that of distilled water group（P0.01）.Conclusion The method of ultrasonic scaling combing with 0.1% of indomethacin or 0.2% of metronidazole irrigation could improve the effects in the treatment of periodontal desease.