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| 正常志愿者与2例累及Wernicke语言区胶质瘤患者听觉语义判断 | |
| 引用本文： | 魏淼,王晓怡,吴陈兴,李少武,江涛,舒华,张忠,戴建平.正常志愿者与2例累及Wernicke语言区胶质瘤患者听觉语义判断[J].中国医学影像技术,2008,24(1):23-26. |
| 作者姓名： | 魏淼 王晓怡 吴陈兴 李少武 江涛 舒华 张忠 戴建平 |
| 作者单位： | 1. 首都医科大学附属北京天坛医院神经影像中心,北京,100050 2. 北京师范大学认知神经科学与学习国家重点实验室,北京,100875 3. 首都医科大学附属北京天坛医院胶质瘤中心,北京,100050 |
| 摘 要： | 目的利用功能磁共振成像技术研究汉语听觉词汇语义判断任务时正常人与Wernicke语言区胶质瘤病人脑的活动情况。方法对15名正常青年受试者和2名胶质瘤累及左侧优势半球Wernicke语言区的病人进行听觉方式呈现汉语词汇语义判断任务的fMRI扫描,由3.0 T MR扫描仪获取数据,并采用AFNI软件进行脑功能区活动图像分析。结果正常志愿者听觉语义判断语言任务激活的主要脑区包括双侧小脑半球、辅助运动区、额下回、颞上回、颞中回、岛叶、左侧顶下小叶、左侧缘上回。两位胶质瘤累及左半球Wernicke区患者的语言任务激活主要脑区包括：双侧小脑半球、辅助运动区、额下回、额中回、颞中回、岛叶、顶下小叶、右侧缘上回、右侧颞上回、右侧额上回。结论2例胶质瘤累及左侧Wernicke区的患者右侧半球激活较正常志愿者组明显增多,以右侧为优势,且左侧Wernicke区的激活减少,代之以肿瘤周边少量激活。 |
| 关 键 词： | 听觉 功能磁共振成像 胶质瘤 Wernicke区 正常志愿者 语言区 胶质瘤 患者 听觉 语义判断 判断任务 功能区 共振研究 involving cases glioma study Functional task judgment semantic auditory 瘤周 优势半球 |
| 文章编号： | 1003-3289（2008）01-0023-04 |
| 收稿时间： | 2007-09-15 |
| 修稿时间： | 2007-12-28 |
Functional MRI study on two glioma cases involving Wernicke's area in auditory semantic judgment task |
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| WEI Miao,WANG Xiao-yi,WU Chen-xing,LI Shao-wu,JIANG Tao,SHU Hu,ZHANG Zhong and DAI Jian-ping.Functional MRI study on two glioma cases involving Wernicke''s area in auditory semantic judgment task[J].Chinese Journal of Medical Imaging Technology,2008,24(1):23-26. | |
| Authors: | WEI Miao WANG Xiao-yi WU Chen-xing LI Shao-wu JIANG Tao SHU Hu ZHANG Zhong and DAI Jian-ping |
| Affiliation: | Imaging Center of Neuroscience,Tiantan Hospital, Capital Medical University, Beijing 100050, China;Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning, Beijing 100875, China;Glioma Center, Tiantan Hospital, Capital Medical University, Beijing 100050, China;Imaging Center of Neuroscience,Tiantan Hospital, Capital Medical University, Beijing 100050, China;Glioma Center, Tiantan Hospital, Capital Medical University, Beijing 100050, China;Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning, Beijing 100875, China;Glioma Center, Tiantan Hospital, Capital Medical University, Beijing 100050, China;Imaging Center of Neuroscience,Tiantan Hospital, Capital Medical University, Beijing 100050, China |
| Abstract: | |
| Keywords: | Auditory Functional magnetic resonance imaging Glioma Wernicke area |
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