不同类型玻璃离子水门汀的氟释放行为与溶解性

背景：改性玻璃离子水门汀提高了玻璃离子水门汀的机械性能、耐磨性和美观性，被逐渐应用于口腔临床的诸多方面，但对改性玻璃离子水门汀的氟释放行为和溶解特性尚不明确。目的：考察FujiⅡ传统型玻璃离子水门汀、Fuji Plus羟基磷灰石改性型玻璃离子水门汀、FujiⅨ金属增强型玻璃离子水门汀及FujiⅡLC光固化树脂改性型玻璃离子水门汀在人工唾液中的氟释放行为与溶解特性。方法：将4种玻璃离子水门汀试样浸没在人工唾液中，采用氟离子选择性电极测定试样浸泡0-28 d的氟释放量；利用分析天平测定试样浸泡3，7，14，28 d的质量，以算溶解率，采用SPSS软件和Origin软件分别进行氟释放量统计学分析和非线性拟合回归分析。结果与结论：各玻璃离子水门汀均在第1天达到最高的氟释放量，在随后几天迅速下降，之后保持稳定，其中FujiⅡLC光固化树脂改性型玻璃离子水门汀的氟释放单日量与累积量，以及溶解率显著高于其他3种玻璃离子水门汀（P ＆lt;0.01）。方程Y=a＋b＊t0.5＋c＊t可较好模拟氟释放累积量变化过程，氟释放累积量与溶解率近似呈正比例关系。FujiⅡLC光固化树脂改性型玻璃离子水门汀达到最高的氟释放累积量与溶解率比值。

Comparison of fluoride release and solubility for different glass ionomer cements

BACKGROUND：Modified glass ionomer cements improve the mechanical properties, abrasion resistance and beauty of traditional glass ionomer cements, and therefore they have been gradualy adopted in many fields of oral clinical application. However, it is not clear that the fluoride release behavior and soluble characteristics. OBJECTIVE：To investigate the fluoride release behavior and soluble characteristics of four glass ionomer cements in artificial saliva： Fuji II tranditional type, Fuji Plus hydroxyapatite modified type, Fuji IX metal modified type, and Fuji II LC light-curing resin modified type. METHODS： For each glass ionomer cement, cylindrical specimens were made and immerged into the artificial saliva. Fluoride release within 0-28 days was measured by using fluoride ion selective electrode. The weight of specimens was measured by using an analytical balance to further calculate the solubility. SPSS and Origin software were used for statistical analysis and nonlinear regression analysis, respectively. RESULTS AND CONCLUSION：For each glass ionomer cement, the fluoride release was peaked at the first day, decreased rapidly for the folowing several days, and then kept relatively stable at the end. The daily amount and accumulation of fluoride of Fuji II LC were significantly higher than those of other three glass ionomer cements （P ＆lt; 0.01）. The formula （Y=a ＋ b＊ t0.5 ＋ c＊ t） could better simulate the variation of fluoride release accumulations, and the fluoride release accumulations were in approximate proportional relationship with solubility. Fuji II LC reached the maximum fluoride release accumulations and the maximum ratio of fluoride release accumulations to solubility.