| 丹参对肺水肿大鼠白细胞介素-8和内皮素的影响 |
| |
| 引用本文： | 吴山,盛延良,蒋志学,孙明.丹参对肺水肿大鼠白细胞介素-8和内皮素的影响[J].中国临床实用医学,2007,1(1). |
| |
| 作者姓名： | 吴山 盛延良 蒋志学 孙明 |
| |
| 作者单位： | 1. 410016,重庆医科大学附属第一医院
2. 154002,黑龙江佳木斯大学 |
| |
| 摘 要： | 目的研究丹参对氯气染毒致大鼠肺水肿时白细胞介素-8和内皮素变化的影响。方法用氯气染毒致大鼠肺水肿,利用放免技术测定大鼠血中白细胞介素-8和内皮素浓度。结果肺水肿时白细胞介素-8和内皮素水平明显上升,应用丹参后均明显下降。结论丹参可降低白细胞介素-8和内皮素水平,从而减轻氯气对肺脏的损伤。
|
| 关 键 词： | 丹参 白细胞介素-8 内皮素 肺脏 水肿 |
Effect of Multiorrhizae on Change of Interleulin-8 and Endothelin in Rat Lung of Edema |
| |
| WU Shan,SHENG Yanliang,JIANG Zhixue,SUN Ming.Effect of Multiorrhizae on Change of Interleulin-8 and Endothelin in Rat Lung of Edema[J].China Clinical Practical Medicine,2007,1(1). |
| |
| Authors: | WU Shan SHENG Yanliang JIANG Zhixue SUN Ming |
| |
| Abstract: | Objective We studied the effect of miltiorrhizae on the change of the concentrations of endothelin(ET-1)and interleukin-8(IL-8)in plasm of rat lung model of edema.Methods The rat lung model of edema was prepared by being exposed to chlorine gas.Radioimmunoassay(RIA)were used to measure the concentrations of ET-1 and IL-8.Results The plasma concentrations of ET-1 and IL-8 in rat exposed to chlorine gas were increased significantly in lung edema group,but that were decreased significantly in miltiorrhizae group.Conclusion Miltiorrhizae can reduce the plasm concentrations of ET-1 and IL-8,miltiorrhizae possessed protective effects on lung edema. |
| |
| Keywords: | miltiorrhizae interleukin-8 endothelin lung edema |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
