梅毒螺旋体抗体筛查及其临床意义

目的研究梅毒螺旋体的感染状况，探讨梅毒螺旋体抗体筛查的现实意义。方法采用酶联免疫分析法（ELIsA）检测梅毒螺旋体抗体，阳性者再使用甲苯胺红不加热血清试验（TRusT）和梅毒螺旋体明胶凝集试验（TPPA）做进一步检测。结果5998例住院患者ELISA法共检测出阳性86例，TPPA法检测出阳性78例，TRUST法检测出阳性22例。高龄（〉70岁）患者的阳性检出率高于其它年龄组。结论住院患者常规筛查梅毒螺旋体抗体可有效检测出隐性梅毒患者，不仅可以早诊断、早治疗，减少医疗纠纷的发生，也可以预防院内交叉感染。

Study on significance of screening serum antibody of Treponema pallidum.

Objective To study the situation of syphilis infection, and to discuss the practical significance of screening antibody of Trepo- nema pallidum. Then positive samples were examined by TRUST（ toluidine red unheated serum test）and TPPA （Treponema pallidum particle ag- glutination） for further testing. Results Altogether 5 998 hospitalized patients were detected by this test, and 86 eases of them were positive by ELISA, and TPPA was positive in 78 cases and positive TRUST in 22 cases. The positive rate in elder patients （ 〉 70 years old） was higher than other age groups. Conclusion Routine screening of hospitalized patients can effectively detect antibody of Treponema pallidum in patients with la- tent syphilis, it is important not only for early diagnosis but also for early treatment, and it may also reduce the occurrence of medical disputes, thus it may prevent the cross infection in hospital.