Argus在儿童活体肝移植术前肝体积评估中的应用

目的探讨磁共振成像(magnetic resonance imaging,MRI)应用心脏专用软件包(Argus)在儿童活体肝脏移植(pediatric living donor liver transplantation,P L D LT)术前移植肝体积评估中的准确性。材料与方法采用M R I对11例PLDLT供体肝脏进行增强扫描,肝静脉期重建数据导入Argus软件计算移植肝体积,并与手术中实际切除肝脏质量进行相关分析,P0.01认为有统计学意义。结果 MRI利用Argus软件测得肝体积平均值为(357.00±72.37)ml,术中实际切除肝脏质量平均值(284.45±61.27)ml,两者之间差异有统计学意义(P0.01),两者存在正相关性(r=0.982,P0.01),建立回归方程W术中肝质量(g)]=0.832×VMR测量肝体积(ml)]-12.46。结论 MRI应用Argus软件可以对移植肝进行术前体积评估,应用回归方程可以较准确地预测移植肝脏质量,为术前移植肝体积评估提供依据。

Evaluate measurement value of liver volume before pediatric living donor liver transplantation by MRI Argus

Objective:To evaluate the accuracy of the application of MRI Argus assessment in liver volume before pediatric living donor liver transplantation (PLDLT).Materials and Methods:Eleven PLDLT donor livers underwent enhanced MRI scanning. Donor liver volumes were calculated with importing venous phase reconstruction data to Argus software, correlation analysis was used with actual removal of the liver weight during the operation.Results:Paired t-test showed there was statistically significant difference`(P<0.01) between liver volume measured by MR Argus software (357.00±72.37) ml and real liver weight in intraoperative actual removal (284.45±61.27) g. Person correlation test showed liver volume measured by MR Argus software had a signiifcantly positive correlation with real liver weight (r=0.982,P<0.001). Graft weight could be expressed in the equation: W real liver weight (g) = 0.832× V liver volume measured by MR Argus-12.46.Conclusion:MRI Argus software is helpful to estimate graft volume before surgery, utilizing the regression equation can accurately forecast the quality of liver transplantation, and providing assessment for preoperative graft volume.