| 一株沃氏葡萄球菌耐药基因的研究 |
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| 引用本文： | 郑新萍,张全斌,张景萍,王萍,金柳,商润萍,马云霞,周永安.一株沃氏葡萄球菌耐药基因的研究[J].山西临床医药,2011(3):206-208. |
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| 作者姓名： | 郑新萍 张全斌 张景萍 王萍 金柳 商润萍 马云霞 周永安 |
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| 作者单位： | 太原市中心医院,山西太原030009 |
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| 基金项目： | 山西省卫生厅科技攻关计划项目 |
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| 摘 要： | 目的：研究沃氏葡萄球菌多重耐药情况和相关机制。方法：采用聚合酶链反应（PCR）法对一株多重耐药沃氏葡萄球菌进行β-内酰胺酶基因、氨基糖苷类修饰酶基因、大环内酯-林可酰胺-链阳菌素B类（MLSB）基因、四环素类基因、糖肽类基因、消毒剂基因检测。结果：PCR结果显示该株的mecA,TEM,ermA,ermC,msrA,msrB,aac（6′）/aph（2″）,qacA基因均为阳性,ant（4′,4″）,aph（3′）-,TetM,vanA,vanB基因均为阴性。结论：该株沃氏葡萄球菌存在多重耐药基因,而且对胺类、胍类消毒剂耐受。
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| 关 键 词： | 沃氏葡萄球菌 β-内酰胺类 氨基糖苷类 耐药基因 |
Study on the strain of staphylococcus warneri with multi-drug resistance gene |
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| ZHENG Xin-ping,ZHANG Quan-bin,ZHANG Jing-ping,WANG Ping,JIN Liu,SHANG Run-ping,MA Yun-xia,ZHOU Yong-an.Study on the strain of staphylococcus warneri with multi-drug resistance gene[J].Shanxi Clinical Medicine,2011(3):206-208. |
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| Authors: | ZHENG Xin-ping ZHANG Quan-bin ZHANG Jing-ping WANG Ping JIN Liu SHANG Run-ping MA Yun-xia ZHOU Yong-an |
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| Affiliation: | (The Central Hospital of Taiyuan,Taiyuan 030009,China) |
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| Abstract: | Objective：To study the instance and mechanism of multi-drug resistance of Staphylococcus warneri.Methods：The genes of multi-drug resistance including beta-lactamase,aminoglycosides modifying enzymes,macrolide-Lincomycin amide-streptogramin（MLSB）,tetracycline,glycopeptides,disinfect resistance were determined by polymerase chain reaction（PCR）.Results：The results of PCR indicated that mecA,TEM,ermA,ermC,msrA,msrB,aac（6′）/aph（2″）,qacA genes were positive,while ant（4′,4″）,aph（3′）-Ⅲ,TetM,vanA,vanB genes were negative.Conclusion：There are multi-drug resistance genes in the strain of Staphylococcus warneri,which resist disinfectant of amines and guanidines. |
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| Keywords: | staphylococcus warneri beta-lactamase aminoglycosides drug resistant gene |
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