盆腔浆液性腺癌43例卵巢形态学观察

目的探讨盆腔浆液性腺癌的卵巢形态特点及其在盆腔浆液性腺癌发生中的意义。方法对43例浆液性腺癌进行分析,其中包括31例卵巢癌与12例腹膜癌,观察卵巢的大体与镜下形态以及合并的病变。结果 43例浆液性腺癌均有卵巢受累,35例(81.4%)为双侧性,42例累及多个脏器。大体观察,卵巢癌组与腹膜癌组卵巢表面有乳头与粘连的比率分别为65.3%与95.2%,切面实性的比率分别为35.2%与81.2%。镜下见卵巢癌与腹膜癌卵巢表面受累的比率分别为22.8%与66.7%,可见残存正常卵巢的比率为66.7%与100%。43例中6例合并子宫浆膜或卵巢子宫内膜异位,1例对侧卵巢考虑子宫内膜异位恶变,2例卵巢包涵腺体未见腺上皮的增生性改变。结论卵巢癌可能是盆腔浆液性腺癌多脏器受累的表现之一,卵巢癌与腹膜癌的卵巢存在很多相似与重叠形态,提示至少部分卵巢癌与腹膜癌有相似的来源,可能为继发性肿瘤。

Morphologic features of ovary in pelvic serous adenocarcinoma

Objective To study the morphologic characteristics of the ovary in pelvic serous adenocarcinoma,and to discuss its significance in the carcinogenesis.Methods Clinicopathologic data were analyzed in 43 cases of pelvic serous adenocarcinoma,including 31 cases of ovarian carcinoma and 12 peritoneal carcinomas.The macroscopic and microscopic features of the ovary and those of associated lesions were observed and investigated.Results The ovary involved by carcinoma was found in all of the 43 cases of pelvic sero...