| 壳聚糖膜的降解与生物相容性研究 |
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| 引用本文： | 卢凤琦,牟忠祥.壳聚糖膜的降解与生物相容性研究[J].生物医学工程学杂志,1998,15(2):183-185. |
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| 作者姓名： | 卢凤琦 牟忠祥 |
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| 作者单位： | 山东医科大学药学系!济南250012(卢凤琦，曹宗顺，庄昭霞)，山东省中医药大学附属医院(牟忠祥)，沈阳药科大学(封锡志) |
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| 摘 要： | 用小鼠作实验动物，研究了壳聚膜的生物降解与生物相容性，结果表明，壳聚糖膜易于生物降解，在植入初期有轻度炎症反应，至１６周后炎症反应基本消失。作为一种新型天然可吸收性生物材料，壳聚糖具有很好的发展应用前景。
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| 关 键 词： | 壳聚糖膜 生物降解 生物相容性 |
Biodegradation and Biocompatibility of a Chitosan Film |
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| Lu Fengqi,Cao Zongshun,Zhuang Zhaoxia,Mou Zhong xiang,Feng xizhi.Biodegradation and Biocompatibility of a Chitosan Film[J].Journal of Biomedical Engineering,1998,15(2):183-185. |
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| Authors: | Lu Fengqi Cao Zongshun Zhuang Zhaoxia Mou Zhong xiang Feng xizhi |
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| Affiliation: | Dept of Pharmacy, Shandong Medical University, Jinan 250012. |
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| Abstract: | The biodegradability and biocompatibility of a chitosan film were investigated in mice. The results showed that chitosan films had a mild inflammatory reaction in the early days of grafting,and after 16 weeks the inflammation basically subsided. Chitosan films were easily biodegraded. Chitosan is a novel natural absorbable medical film material and has a good developmental prospect. |
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| Keywords: | Chitosan film Biodegradation Biocompatibility |
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