178例肺亚厘米结节(直径≤8 mm)影像学与临床病理分析

目的探讨肺亚厘米结节(直径≤8 mm)的影像学特点和临床病理特征。方法回顾性分析178例肺亚厘米结节的影像学特点和临床病理特征,并复习相关文献。结果术后病理证实,178例肺亚厘米结节中,良性结节110例(61.8%),恶性结节68例(38.2%)。实性结节65例,其中良性结节60例(92.3%),恶性结节5例(7.7%);混合磨玻璃结节37例,其中良性结节24例(64.9%),恶性结节13例(35.1%);纯磨玻璃结节76例,其中良性结节26例(34.2%),恶性结节50例(65.8%)。患者性别、结节位置、直径在良性组和恶性组间差异有统计学意义(P<0.05);患者年龄在两组间差异无统计学意义(P>0.05)。毛刺征和血管集束征在良性和恶性组间差异有统计学意义(P<0.05);分叶征、胸膜凹陷征、支气管充气征、空泡征在两组间差异无统计学意义(P>0.05)。结论直径≤8 mm的肺亚厘米结节以良性结节居多,部分高危CT征象在良性结节中也有出现,临床医师应注意鉴别。

Imaging and clinicopathological analysis of 178 case of pulmonary sub-centimeter nodules less than 8 mm in diameter

Purpose To investigate the imaging and clinicopathological features of pulmonary sub-centimeter nodules less than 8 mm in diameter.Methods The imaging and clinicopathological feature of 178 cases of pulmonary sub-centimeter nodules less than 8 mm in diameter were analyzed retrospectively,and the relevant literatures were also reviewed.Results Postoperative pathology confirmed that among 178 cases of pulmonary sub-centimeter nodules,110 cases(61.8%)were benign nodules and 68 cases(38.2%)were malignant nodules.Among 65 cases of solid nodules,there were 60 cases of benign nodules(92.3%)and 5 cases of malignant nodules(7.7%).Of 37 cases of mixed ground glass nodules,24 cases were benign nodules(64.9%)and 13 cases were malignant nodules(35.1%).Among 76 cases of pure ground glass nodules,there were 26 cases of benign nodules(34.2%)and 50 cases of malignant nodules(65.8%).There were statistically significant differences in gender,location and diameter of nodules between benign and malignant groups(P<0.05),but there was no significant difference in age between the two groups(P>0.05).There were statistically significant differences in spicule sign and vessel convergence sign between benign and malignant groups(P<0.05),however,there was no significant difference in lobulation sign,pleura retraction sign,bronchial inflation sign,vacuole sign between the two groups(P>0.05).Conclusion Most of the pulmonary sub-centimeter nodules less than 8 mm in diameter are benign nodules,and some high-risk CT signs are also found in benign nodules.Clinicians should pay more attention to this nodules.