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人细胞色素P450 前mRNA的可变剪接研究进展
引用本文:诸葛坚,余应年.人细胞色素P450 前mRNA的可变剪接研究进展[J].中国病理生理杂志,2005,21(2):403-407.
作者姓名:诸葛坚  余应年
作者单位:浙江大学医学院病理生理学教研室, 浙江 杭州 310031
基金项目:国家自然科学基金资助项目 (No .396 70 80 1),浙江省自然科学基金资助项目 (No.396 4 6 7)
摘    要:Human genes typically contain multiple introns, and in many cases the exons can be joined more than one way to generate multiple rnRNAs, encoding distinct protein isoforms. This process is called alternative splicing. The article summarized the human cytochrome P450 pre-mRNA alternative splicing and their regulatory mechanism and impacts on biological functions.

关 键 词:细胞色素P450  可变剪接  RNA  
文章编号:1000-4718(2005)02-0403-05
收稿时间:2003-8-13
修稿时间:2003-10-27

Progress on research of the alternative splicing of human cytochrome P450 pre-mRNA
ZHUGE Jian,YU Ying-nian.Progress on research of the alternative splicing of human cytochrome P450 pre-mRNA[J].Chinese Journal of Pathophysiology,2005,21(2):403-407.
Authors:ZHUGE Jian  YU Ying-nian
Affiliation:Department of Pathophysiology, Zhejiang University School of Medicine, Hangzhou 310031, China
Abstract:Human genes typically contain multiple introns, and in many cases the exons can be joined more than one way to generate multiple mRNAs, encoding distinct protein isoforms. This process is called alternative splicing. The article summarized the human cytochrome P450 pre mRNA alternative splicing and their regulatory mechanism and impacts on biological functions.
Keywords:Cytochrome P  450  Alternative splic ing  RNA  messenger
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