薏苡仁油回流提取工艺参数优化及其动力学研究

探索加热回流法提取薏苡仁油的最佳工艺条件,并对提取过程进行深入探讨。采用单因素法考察溶剂、料液比、药材粒径、提取时间等对薏苡仁油提取率的影响,在此基础上研究其提取动力学。结果表明薏苡仁油较佳的提取条件为采用丙酮作为溶剂,液固比7倍,药材平均粒径0.25 mm,提取3 h。动力学研究表明,粒径较小时(0.25~0.83 mm),薏苡仁油的提取动力学符合二阶溶出动力学模型,即减小药材粒径,可明显增加有效成分的提取率。

Optimization and kinetics for the refluxing extraction process of Coix seed oil

The refluxing extraction process of Coix seed oil and the kinetics of the process were investigated.Parameters including solvents,particles size,and extraction time affecting the recovery rate were studied and the optimal extraction process was determined.The extraction kinetics were studied.The optimal refluxing extraction conditions were as follows：acetone solvent,acetone to material ratio 7∶1,reflux time 3 h,particle size 0.25 mm.When the partical size was less than 0.83 mm,the kinetics fit the second order model.The result could be used to optimize and control the extraction process of Coix seed oil.