| 波罗的海放线菌的多样性 |
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| 引用本文： | 姜怡,曹艳茹,王茜,靳荣线.波罗的海放线菌的多样性[J].微生物学报,2011,51(11):1461-1467. |
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| 作者姓名： | 姜怡 曹艳茹 王茜 靳荣线 |
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| 作者单位： | 1. 云南大学微生物研究所,西南微生物多样性教育部重点实验室,昆明650091
2. 云南大学微生物研究所,西南微生物多样性教育部重点实验室,昆明650091;西北农林科技大学资源环境学院,杨陵712100 |
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| 基金项目： | 国家自然科学基金(30900002，21062028);the“Kieler Wirkstoff-Zentrum am IFM-GEOMAR”,which is supported by the Ministerium für Wissenschaft，Wirtschaft und Verkehr des Landes Schleswig-Holstein (Germany);国家重大科技专项创新药物筛选体系及新技术平台建设(2009ZX09302-003);美国国家卫生研究院资助项目(1P41GM086 |
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| 摘 要： | 摘要:【目的】为了探索海洋放线菌的多样性，为发现新的药物先导化合物提供新菌源，我们分析了波罗的海的放线菌多样性及生物活性。【方法】采集100 份底泥样品，用7 种培养基分离放线菌809 株;去掉相同菌株后，选择280 株代表菌进行了初步分类鉴定;采用琼脂扩散法，检测了它们对5 种细菌、真菌的抗菌活性;用API ZYM system 测定了21 种酶的活性。【结果】用海藻糖-脯氨酸培养基和HV 培养基分离的放线菌中，稀有放线菌占60% 和63% ;波罗的海的放线菌有15 个属，其中3 个属是首次从海洋中分离
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| 关 键 词： | 关键词: 放线菌多样性，生物活性，波罗的海 |
| 收稿时间： | 2011/4/21 0:00:00 |
| 修稿时间： | 2011/6/24 0:00:00 |
Diversity of cultured actinomycete in the Baltic Sea |
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| Yi Jiang,Yanru Cao,Qian Wang and Rongxian Jin.Diversity of cultured actinomycete in the Baltic Sea[J].Acta Microbiologica Sinica,2011,51(11):1461-1467. |
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| Authors: | Yi Jiang Yanru Cao Qian Wang and Rongxian Jin |
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| Affiliation: | Yi Jiang1*,Yanru Cao1,2,Qian Wang1,Rongxian Jin1 1 Key Laboratory of Microbial Diversity in Southwest China,Ministry of Education and Laboratory for Conservation and Utilization of Bio-Resources,Yunnan Institute of Microbiology,Yunnan University,Kunming 650091,China 2 College of Resources and Environment,Northwest A & F University,Yangling 712100,China |
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| Abstract: | Objective] Actinomycetes(actinobacteria) are getting more and more recognized as a natural source for new drug exploration.In order to find new lead compounds,the diversity and selected bioactivities of cultured actinomycetes in the Baltic Sea(Germany) were investigated.Methods] One hundred sediment samples were collected from south of the Baltic Sea,of which 809 purified cultures of actinomycetes were obtained by using 7 media.The phylogenetic analysis of 280 selected strains based on 16S rRNA gene seque... |
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| Keywords: | actinomycete diversity bioactivities Baltic Sea |
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