婴幼儿轮状病毒肠炎48例病原学检测及治疗

轮状病毒是婴幼儿秋冬季腹泻的最常见的病原。我们用ＥＬＩＳＡ试剂盒对５４例大便常规检查无ＷＢＣ或偶见的疑似轮状病毒腹泻患儿进行了轮状病毒病原学检测，从中检出轮状病毒阳性患儿４８例，被确诊为轮状病毒肠炎。结果显示粪便中轮状病毒滴度越高，其临床症状也相应越重。此４８例患儿均采用病毒唑、双歧杆菌活菌制剂、补液纠正脱水等综合治疗，其中３０例辅以消化道粘膜保护剂思密达治疗，治疗组显效率为６０％，而对照组为１１．１％，经ｔ检验两组间显效率及总有效率均有非常显著性差异。表明思密达用于轮状病毒肠炎的治疗是一种较为有效的方法。

Pathogenic Examination and Therapy for 48 Cases of Infant Rotavirus Enteritis

Rotavirus is a main pathogen of infant diarrhea in autumn and winter.54 cases of diarrhea suspected of Rotavirus enteritis were examinated for pathogen by using the ELISA kit for detection of Rotavirus in their fecal specimens in which were free or few WBC according to routine fecal examination.48 cases were positive in ELISA tests and were defined to Rotavirus enteritis.The results revealed that the higher the virus titer,the more serious the clinical symptom.The 48 cases were all treated synthetically using RIBAVIRINI,BIFIDOBIOGEN,and rehydrating.Thirty of these cases were also treated by SMECTA,a protective agent for gastrointestinal mucosa,and the others as controls.The effective rate was 60% in test group and 11.1% in control group.It was very significant between the groups based on the t test.It is suggested that the SMECTA should be a effective medicine for therapy of Rotavirus enteritis.