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方兴未艾的古代DNA的研究
引用本文:蔡胜和,杨焕明.方兴未艾的古代DNA的研究[J].遗传,2000,22(1):41-46.
作者姓名:蔡胜和  杨焕明
作者单位:1.中国协和医科大学基础医学院中国医学科学院基础医学研究所,北京 100005 2.中国科学院遗传研究所人类基因组中心,北京 100810 1.Department of Genetics,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences and Peking Medical College,Beijing 100005 2.Center of Human Genome,Institute of Genetics,Chinese Academy of Science,Beijing 100101
基金项目:国家杰出青年科学基金!(39425011)资助项目
摘    要:保留在古代生物遗骸中的遗传物质DNA是一种重要的遗传资源。古代DNA的研究对于了解包括人类在内的各种生物的起源、进化和迁徙有重要意义。古代DNA的研究有其自身的特点,并且已经取得一系列重要成就。本文综述古代DNA研究的历史、方法和进展。 Abstract:DNA present in ancient samples can be recovered,amplified and analysed.It opens a new window for genetic analysis in many different disciplines,such as anthropology,archaeology,human population genetics,animal and plant evolutionary taxonomy and forensic science.In general,ancient DNA is rare in quantity,damaged in quality.To ensure the reproducibility and reliability of the results,great cares should be taken,such as various measurements against contamination and phylogenetic analysis of ancient DNA sequences.In this paper we review recovery,amplification and analysis of ancient DNA,also discuss the guidelines to ensure the authenticity of ancient DNA and the recent advances in ancient DNA study.

关 键 词:古代DNA  PCR  Ancient  DNA  PCR  可靠性  Key  words  

Emerging Field of Ancient DNA Study
CAI Sheng-he,YANG Huan-ming.Emerging Field of Ancient DNA Study[J].Hereditas,2000,22(1):41-46.
Authors:CAI Sheng-he  YANG Huan-ming
Abstract:DNA present in ancient samples can be recovered,amplified and analysed.It opens a new window for genetic analysis in many different disciplines,such as anthropology,archaeology,human population genetics,animal and plant evolutionary taxonomy and forensic science.In general,ancient DNA is rare in quantity,damaged in quality.To ensure the reproducibility and reliability of the results,great cares should be taken,such as various measurements against contamination and phylogenetic analysis of ancient DNA sequences.In this paper we review recovery,amplification and analysis of ancient DNA,also discuss the guidelines to ensure the authenticity of ancient DNA and the recent advances in ancient DNA study.
Keywords:Ancient DNA  PCR  Authenticity
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