妊娠期未足月胎膜早破病因分析

目的:分析妊娠期未足月胎膜早破孕妇发生孕周及病因,为临床处治提供指导。方法:103例未足月胎膜早破孕妇患者按孕周分为两组,对他们的临床资料进行回顾性研究。结果:2组在患者平均年龄及反应感染的血指标没有明显区别,均未提示入院时存在感染。103例PPROM患者破膜孕周主要发生在孕32-36+6周,双胎及生殖系统微生物感染为破膜的主要原因,终止妊娠原因主要为羊水过少。宫颈管微生物培养菌主要为GBS,其余可见的有白色念珠菌,表皮葡萄球菌,弓形虫,及其他厌氧菌。结论:生殖系统炎症尤其是GBS感染是导致未足月胎膜早破的重要原因;双胎也是导致PPROM发尤其是生的高危因素,减少胎膜早破,也有助于降低剖宫产率,改善胎儿结局。

Clinical Analysis on Preterm Premature Rupture of Membranes

Objective:To investigate the athogenesis of pretermpremature rupture of membranes (PPROM) and to provide guidelines for clinical treatment.Methods:The 103 PPROMpregnant women collected fromour hospital were divided into two groups according to their gestational age. Their clinical data were retrospectively analyzed.Results:The patients in the two groups had no significant differences in the average age and the blood indicators of infection at admission. They had no infection at admission. The rupture of membranes occurred mainly at gestational age of 32-36 + 6 weeks. Twins and microbial infections of the reproductive system became the main causes for rupture of membranes. Termination of pregnancy was decided mainly for oligohydramnios. Cervical microbiological culture bacteria were mostly GBS, and the rests visible were Candida albicans,Staphylococcus epidermidis ,Toxoplasma gondii , and other anaerobic bacteria.Conclusion:Reproductive system inflammation, especially GBS infection, was the most important risk factor for PPROM. Positive control can effectively reduce the incidence. Twins were also risk factors for PPROM. Reducing the premature rupture of membranes could help reduce the cesarean section rate and improve fetal outcomes.