不同切口超声乳化术联合小梁切除术对白内障合并青光眼患者视力、角膜内皮细胞及生活质量的影响

摘要 目的：探讨不同切口超声乳化术联合小梁切除术对白内障合并青光眼患者视力、角膜内皮细胞及生活质量的影响。方法：回顾性分析2018年4月~2019年7月期间我院收治的150例白内障合并青光眼患者的临床资料，根据手术方式的不同分为A组（n=75，单切口超声乳化术联合小梁切除术）和B组（n=75，双切口超声乳化术联合小梁切除术）。比较两组患者眼压、裸眼视力、最佳矫正视力、角膜内皮细胞、生活质量及并发症。结果：两组术后3个月健康调查简表(SF-36)各维度评分均升高，且B组高于A组（P<0.05）。两组术后3个月眼压均降低，且B组低于A组（P<0.05）；两组术后3个月裸眼视力和最佳矫正视力均升高，且B组高于A组（P<0.05）。两组术后3个月角膜内皮细胞面积均增加，但B组小于A组（P<0.05）；角膜内皮细胞密度均下降，但B组高于A组（P<0.05）。B组术后并发症总发生率低于A组（P<0.05）。结论：与单切口超声乳化术联合小梁切除术相比，白内障合并青光眼患者采用双切口超声乳化术联合小梁切除术治疗，在改善患者眼压、裸眼视力、最佳矫正视力、角膜内皮细胞、生活质量及减少并发症发生率方面的效果更佳。

Effect of Different Incision Phacoemulsification Combined with Trabeculectomy on Vision, Corneal Endothelial Cells and Quality of Life in Cataract Patients with Glaucoma

ABSTRACT Objective: To investigate the effect of different incision phacoemulsification combined with trabeculectomy on vision, corneal endothelial cells and quality of life in cataract patients with glaucoma. Methods: The clinical data of 150 patients with cataract and glaucoma who were admitted to our hospital were analyzed retrospectively from April 2018 to July 2019. They were divided into group A (n=75, single incision phacoemulsification combined with trabeculectomy) and group B (n=75, double incision phacoemulsification combined with trabeculectomy) by different operation methods. The intraocular pressure, naked vision, best corrected vision, corneal endothelial cells, quality of life and complications were compared between the two groups. Results: The scores of health survey form (SF-36) in the two groups were higher than those in group A (P < 0.05). The intraocular pressure in group B was lower than that in group A (P < 0.05), and the uncorrected visual acuity and the best corrected visual acuity in group B were higher than that in group A (P < 0.05). The area of corneal endothelial cells in group B was smaller than that in group A (P < 0.05), and the density of corneal endothelial cells in group B was lower than that in group A (P < 0.05). The total incidence of postoperative complications in group B was lower than that in group A (P< 0.05). Conclusion: Compared with single incision phacoemulsification combined with trabeculectomy, double incision phacoemulsification combined with trabeculectomy is more effective in improving intraocular pressure, naked eye vision, best corrected vision, corneal endothelial cells, quality of life and reducing complications.