视觉功能训练联合托吡卡胺滴眼液治疗假性近视的临床疗效观察

摘要 目的：探讨视觉功能训练联合托吡卡胺滴眼液在治疗假性近视中的临床疗效。方法：选取中国人民解放军陆军特色医学中心眼科和重庆佑佑宝贝妇儿医院眼科2019年2月至2019年8月收治的400例假性近视患儿作为研究对象，将其随机分为对照组和观察组(n=200)。对照组给予滴眼液缓解眼疲劳治疗，观察组则采用视觉功能训练联合托吡卡胺滴眼液治疗。比较两组患儿治疗前及治疗2个月、6个月后裸眼视力、眼轴长度、屈光度、正相对调节量和视疲劳评分的变化。结果：治疗2个月和6个月后，观察组患儿裸眼视力分别为(0.75±0.05)和(0.81±0.04)，较对照组显著上升(P<0.05)；屈光度分别为(+0.05±0.50)和(+0.06±0.48)，明显高于对照组(P<0.05)；正相对调节量检测结果依次是(-1.98±0.07)和(-2.51±0.24)，较对照组明显增加(P<0.05)。两组患儿视觉感知双眼视功能均有明显改善，其中观察组视觉功能恢复显著高于对照组(P<0.05)。视疲劳调查显示观察组患儿视疲劳评分分别为(6.90±0.89)分和(3.91±0.89)分，显著低于对照组(P<0.05)。结论：视觉功能训练联合托吡卡胺滴眼液治疗能有效提高患儿裸眼视力、改善屈光度、正相对调节量和视觉感知功能，从而减少视疲劳，预防近视。

Clinical Observation of Visual Function Training Combined with Topicamide Eye Drops in the Treatment of Pseudomyopia

ABSTRACT Objective: To investigate the clinical effect of visual function training combined with topicamide eye drops in the treatment of pseudo myopia. Methods: 400 cases of children with pseudomyopia admitted to the ophthalmology department of the army characteristic medical center of the Chinese people''s liberation army and the ophthalmology department of Chongqing you baby women''s and children''s hospital were selected as the research objects from February 2019 to Agust 2019. They were randomly divided into the control group and the observation group (n=200). The control group was treated with eye drops to relieve eye fatigue, while the observation group was treated with visual training combined with compound topicamide eye drops. The visual acuity, axial length, diopter, positive and relative adjustment, and visual fatigue score were measured and compared between two groups before and after treatment. Results: After 2 month and 6 months of treatment, the visual acuity of the children in the observation group was (0.75±0.05) and (0.81±0.04), which was significantly higher than that of the control group (P<0.05). The diopters of children were (+0.05±0.50) and (+0.06±0.48), respectively, and the improvement was significantly better than that of the control group (P<0.05). The test results of the positive relative regulation quantity were (-1.98±0.07) and (-2.51±0.24) respectively, which were significantly better compared with the control group(P<0.05). The visual perception binocular visual function of two groups improved significantly, and the visual function recovery of observation group was significantly higher than that of control group (P<0.05). The investigation of visual fatigue showed that the scores of visual fatigue in the observation group were (6.90±0.89) and (3.91±0.89), which were significantly lower than those in the control group (P<0.05). Conclusion: Visual function training combined with compound topicamide eye drops could effectively improve children''s naked eye vision, and promote diopter, positive relative adjustment and V visual perception function, which reduced visual fatigue and prevented myopia.