| 近红外光谱技术在猫脑射频热凝毁损中的应用研究 |
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| 引用本文： | 张立国,杨天明,钱志余,潇笛,郭凯,刘华亭.近红外光谱技术在猫脑射频热凝毁损中的应用研究[J].现代生物医学进展,2011,11(1):71-74. |
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| 作者姓名： | 张立国 杨天明 钱志余 潇笛 郭凯 刘华亭 |
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| 作者单位： | 1. 东南大学附属中大医院,神经外科,江苏,南京,210009
2. 南京航空航天大学,生物医学工程系,江苏,南京,210016 |
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| 基金项目： | 国家高技术研究863计划基金资助(2008AA02Z438) |
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| 摘 要： | 目的:探索近红外光谱(nears)技术用于立体定向靶点毁损术中实时监测的可行性。方法:利用猫脑建立体内不同毁损时间、温度下的毁损灶体积模型,通过病理检测及近红外光谱仪观察并记录脑组织靶点毁损时的NIRS尤其是优化散射系数()的变化情况。结果:不同温度、不同时间温度点下NIRS出现特征性变化曲线。并建立时间、温度及三维模型。结论:利用NIRS实时活体在位监测猫脑射频神经核团毁损术是科学、可行的,优化散射系数是监测的良好指标,比以往单凭经验的作法更科学、更准确。
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| 关 键 词： | 近红外光谱技术 优化散射系数 立体定位技术 猫脑 |
Application of near-infrared spectroscopy technology in cat brain
radiofrequency |
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| ZHANG Li-guo,YANG Tian-ming,QIAN Zhi-yu,XIAO Di,GUO Kai,LIU Hua-ting.Application of near-infrared spectroscopy technology in cat brain
radiofrequency[J].Progress in Modern Biomedicine,2011,11(1):71-74. |
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| Authors: | ZHANG Li-guo YANG Tian-ming QIAN Zhi-yu XIAO Di GUO Kai LIU Hua-ting |
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| Affiliation: | 1(1 Department of Neurosurgery,Zhongda Hospital,Southeast University,Nanjing 210009,China; 2 Department of Biomedical Engineering,Nanjing University of Aeronautics and Astronautics,Nanjing 210016,China) |
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| Abstract: | Objective: To investigate the feasibility of near-infrared spectroscopy(NIRS) technology i monitor real-time target in the stereotactic destruction technology.Methods: In vivo volume models of RF lesion with different lesion time and temperature were es-tablished(,adult cats in vivo).The height and maximum lesion diameter of adult cats in vivo were detected by pathology testing and MRI.Target destruction in near-infrared spectroscopy monitoring: Changes in brain tissue,the changes of reduced scattering coef... |
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| Keywords: | Near-infra red spectroscopy Reduced scattering coefficient Stereotactic technology Cats |
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