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| 延胡索的化学成分研究(英文) | |
| 引用本文： | 石俊敏,韩伟立,叶文才,陈锡桥,王一涛,张庆文.延胡索的化学成分研究(英文)[J].天然产物研究与开发,2011,23(4):647-651. |
| 作者姓名： | 石俊敏 韩伟立 叶文才 陈锡桥 王一涛 张庆文 |
| 作者单位： | 1. 澳门大学中华医药研究院,澳门;暨南大学中药及天然药物研究所;暨南大学中药药效物质基础及创新药物研究广东省重点实验室,广州510632; 2. 暨南大学中药及天然药物研究所;暨南大学中药药效物质基础及创新药物研究广东省重点实验室,广州510632 3. 澳门大学科技学院,澳门 4. 澳门大学中华医药研究院,澳门 |
| 基金项目： | supported by the Macao Science and Technology Development Fund(029/2007/A2); Research committee of University of Macau(RG075/06-07S/WYT/ICMS and UL016/09-Y1/CMS/WYT01/ICMS) |
| 摘 要： | 采用现代分离技术和方法,从延胡索根茎中分离得到17个化合物,通过波谱分析鉴定其结构。包括11个生物碱类化合物,二氢白屈菜红碱(1)、去氢紫堇碱(2)、四氢非洲防己胺(3)、异紫堇球碱(4)、紫堇碱(5)、四氢黄连碱(6)、药根碱(7)、黄连碱(8)、小檗碱(12)、巴马汀(13)和延胡索乙素(14);2个蒽醌类化合物,大黄素(9)和大黄素甲醚(10);1个三萜类化合物,即3β-羟基-齐墩果烷-111,3(18)-二烯-28-酸(11)和3个甾醇类化合物,豆甾醇(15)、β-谷甾醇(16)和胡萝卜苷(17)。其中,化合物9～11首次从该属植物中分离得到,1首次从该种中分离得到。 |
| 关 键 词： | 延胡索 异喹啉类生物碱 蒽醌 三萜 |
Phytochemical Investigation of Corydalis yanhusuo |
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| SHI Jun-min,HAN Wei-li,YE Wen-cai,CHAN Shek-kiu,WANG Yi-tao,ZHANG Qing-wen.Phytochemical Investigation of Corydalis yanhusuo[J].Natural Product Research and Development,2011,23(4):647-651. | |
| Authors: | SHI Jun-min HAN Wei-li YE Wen-cai CHAN Shek-kiu WANG Yi-tao ZHANG Qing-wen |
| Affiliation: | SHI Jun-min1,2,3,HAN Wei-li2,YE Wen-cai2,CHAN Shek-kiu4,WANG Yi-tao1,ZHANG Qing-wen1 1Institute of Chinese Medical Sciences,University of Macau,Taipa,Macau,2Institute of Traditional Chinese Medicine and Natural Products,Jinan University,3Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research,Guangzhou 510632,China,4Faculty of Science and Technology |
| Abstract: | Seventeen compounds have been isolated from Corydalis yanhusuo W.T.Wang.Their structures were deduced on the basts of their physicochemical properties and spectroscopic data.These compounds,including eleven alkaloids,two anthraquinones,a triterpenoid and three steroids,were identified as dihydrochelerythrine ( 1 ),dehydrocorydaline (2),tetrahydrocolumbamine (3),isocorrybulbine (4),corydaline (5),tetrahydrocoptisine (6),jatrorrhizine (7),coptisine (8),emodin (9),physcion ( 10 ),3β-hydroxy-olean-11,13 ( 18 ) -dien-28-oic acid ( 11 ),berberine ( 12 ),palmatine ( 13 ),tetrahydropalmatine (14),stigmasterol ( 15 ),β-sitosterol ( 16 ),and daucosterol ( 17 ).Compounds 9-11 were isolated from genus Corydalis for the first time,and 1 was firstly isolated from this species. |
| Keywords: | Corydalis yanhusuo isoquinoline alkaloid anthraquinone triterpenoid |
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