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基于离散单元法多孔陶瓷微球骨支架的微观结构分析
引用本文:魏庆华,汪焰恩,杨明明,魏生民.基于离散单元法多孔陶瓷微球骨支架的微观结构分析[J].工具技术,2013(12):8-12.
作者姓名:魏庆华  汪焰恩  杨明明  魏生民
作者单位:西北工业大学
基金项目:国家自然科学基金(51175432,50905147);西北工业大学博士论文创新基金资助(201213);西北工业大学研究生创业种子基金资助(Z2013043);陕西省自然科学基金(2011JQ7005);中国博士后科学研究基金(200902606,2008044193);西北工业大学新人新方向(10GH0133);西北工业大学基础研究基金(JC20100230)
摘    要:人工骨支架的孔隙率是评价体液在人工骨内部循环和细胞生长能力的重要参数,利用离散单元法分析模拟人工骨支架制备过程中HA微球的堆积过程,实现了对堆积内部微观情况的预测。本文以PFC3D软件为平台对HA石微球人工骨支架的微观结构进行了模拟仿真,从而通过改变HA微球和可速溶性小球的数量比及半径值,实现孔隙率可控,得出配位数为6时,HA微球人工骨支架的孔隙率为0.59,在满足力学性能的条件下,与人骨组织的孔隙率最为接近。

关 键 词:人工骨支架  羟基磷灰石  孔隙率  配位数  离散单元法

Research of Artificial Bone Material Microstructure Based on Discrete Element Method
Wei Qinghua,Wang Yanen,Yang Mingming,Wei Shengmin.Research of Artificial Bone Material Microstructure Based on Discrete Element Method[J].Tool Engineering(The Magazine for Cutting & Measuring Engineering),2013(12):8-12.
Authors:Wei Qinghua  Wang Yanen  Yang Mingming  Wei Shengmin
Affiliation:Wei Qinghua, Wang Yanen, Yang Mingming, Wei Shengmin
Abstract:The porosity of artificial bone scaffold is an important parameter that affects the fluid circulation in bone cells and internal growth capacity in the body. In the artificial bone scaffold fabrication process, using discrete element method to simulate the accumulation of HA microspheres, realize the internal microstrueture prediction of accumulation. Simulating the artificial bone scaffold microstructure based on the platform of PFC3D software. Thus by changing the number ratio and radius of HA mierospheres and soluble balls, achieve the porosity is controllable. Have obtained that the porosity of HA microsphere artificial bone scaffold is 0.59, meanwhile the coordination number is 6.
Keywords:artificial bone scaffold  HA  porosity  coordination number  discrete element method
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