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液相色谱-串联质谱法测定牛奶中舒巴坦和他唑巴坦
引用本文:郭启雷,王浩,杨红梅,刘艳琴,曹红.液相色谱-串联质谱法测定牛奶中舒巴坦和他唑巴坦[J].质谱学报,2009,30(Z1):162-164.
作者姓名:郭启雷  王浩  杨红梅  刘艳琴  曹红
作者单位:国家食品质量安全监督检验中心,北京 100094
摘    要:


Determination of Salbactam and Tazobactam in Milk by LC-MS/MS
GUOQi-lei,WANGHao,YANGHong-mei,LIUYan-qin,CAOHong.Determination of Salbactam and Tazobactam in Milk by LC-MS/MS[J].Journal of Chinese Mass Spectrometry Society,2009,30(Z1):162-164.
Authors:GUOQi-lei  WANGHao  YANGHong-mei  LIUYan-qin  CAOHong
Affiliation:National Food Quality & Safety Supervision and Inspection Center, Beijing 100094, China
Abstract:A triple quadrupole liquid chromatography tandem mass spectrometry method is presented for the quantitative determination and confirmation of salbactam and tazobactam, the inhibitors of β-lactamase in milk. Milk was extracted with methanol, and the extracts were analyzed by LC-MS/MS in negative mode. The LOQs of salbactam and tazobactam in milk are 10 μg•L-1 and 100 μg•L-1, respectively.
Keywords:salbactam  tazobactam  β-lactamase  antibiotics  
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