Visual function,ocular surface integrity and symptomatology of a new extended depth-of-focus and a conventional multifocal contact lens |
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| Affiliation: | 1. Department of Optometry and Vision, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain;2. Department of Biochemistry and Molecular Biology, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain;1. Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain;2. Department of Ophthalmology, Vithas Medimar International Hospital, Alicante, Spain;1. Health Sciences University Samsun Training and Research Hospital, Department of Ophthalmology Samsun, Turkey;2. Department of Ophthalmology, Van Yuzuncu Yil University, Faculty Of Medicine, Turkey;1. Pacific University College of Optometry, Forest Grove, OR, USA;2. Eye-Contact-Lens Research & Education, Amsterdam, The Netherlands;3. Optimec Systems Ltd, Malvern, United Kingdom;1. Ophthalmic Research Group, School of Life and Health Sciences, Aston University, Birmingham, United Kingdom;2. Specsavers, New Malden, London, United Kingdom;1. Laboratory of Bionics and Experimental Medical Biology, Department of Bionics and Bioimpendance, Poznań University of Medical Sciences, Parkowa 2, 60-775, Poznań, Poland;2. Laboratory of Vision and Neuroscience, NanoBioMedical Center, Adam Mickiewicz University of Poznań, Umultowska 85, 61-614 Poznań, Poland;3. Laboratory of Vision Science and Optometry, Faculty of Physics, Adam Mickiewicz University of Poznań, Umultowska 85, 61-614 Poznań, Poland;4. University of Milano Bicocca, Department of Materials Science, R. Cozzi 55, I-20125 Milan, Italy;5. School of Life and Health Sciences, Aston University, Aston Triangle, B4 7ET, Birmingham, UK;6. Department of Ophthalmology, Chair of Ophthalmology and Optometry, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806 Poznań, Poznań, Poland;1. School of Optometry and Vision Science, University of Bradford, Bradford, UK;2. Wolfson Centre for Applied Health Research, Bradford Teaching Hospitals, Bradford, UK;3. School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK |
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| Abstract: | PurposeTo evaluate visual function, ocular surface integrity and dry eye symptoms with an extended depth-of-focus (EDOF) design and a conventional multifocal (MF) contact lens (CL) after 15 days of wear.MethodsA crossover single mask randomised clinical trial was conducted including 30 presbyopes who used an EDOF and a conventional MF CL (Biofinity MF) for 15 days each. Defocus curves, depth-of-focus range, contrast sensitivity (CS) under photopic and mesopic conditions (with and without glare) and subjective perception of halos and glare were evaluated. The ocular surface was evaluated through non-invasive Keratograph tear breakup time (NIKBUT), averaged tear breakup time (NIKBUT-avg), tear meniscus height (TMH), bulbar and limbal redness, and conjunctival and corneal staining. Dry eye symptoms were assessed with the OSDI questionnaire.ResultsNo statistically significant differences were found for defocus curves or depth-of-focus between the two CLs (both p > 0.05). Subjective perception of halos and glare was not significantly different between CLs. Statistically significant differences were observed for CS under mesopic conditions for low spatial frequencies (p = 0.008). None of the CL produced significant changes in NIKBUT, NIKBUT-avg, TMH or redness. No change in conjunctival staining was observed in 76.7 % and 73.3 % of participants for EDOF and Biofinity MF, respectively. No change in corneal staining was observed in 86.7 % and 83.3 % of participants for EDOF and Biofinity MF, respectively. No changes were observed in the symptomatology measured with OSDI questionnaire (p > 0.05).ConclusionsBoth CL for presbyopia offer good visual quality, preserve the ocular surface integrity and provide the patient with similar symptomatology levels after 15 days of lens wear. |
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| Keywords: | Extended depth-of-focus Multifocal contact lens Presbyopia |
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