Characteristic of polysaccharides from Flammulina velutipes in vitro digestion under salivary,simulated gastric and small intestinal conditions and fermentation by human gut microbiota |
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| Authors: | Anxiang Su Gaoxing Ma Minhao Xie Yang Ji Xiangfei Li Liyan Zhao Qiuhui Hu |
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| Affiliation: | 1. College of Food Science and Technology, Nanjing Agricultural University, Nanjing, 210095 Jiangsu, China;2. College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, 210023 Jiangsu, China |
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| Abstract: | In this study, in vitro digestion and fermentation of Flammulina velutipes -derived polysaccharides (FVP) were investigated. It was found that FVP mainly consisted of 48.45% glucose, 15.40% mannose, 14.60% xylose, 11.80% fucose and 9.90% galactose. The -human saliva, simulated gastric and small intestinal juices conditions did not break down the FVP. Based on in vitro fermentation tests, FVP modulated the composition of gut microbiota by elevating the amounts of Bifidobacteriaceae and Bacteroidaceae and reducing the numbers of genera Lachnospiraceae and Enterococcaceae. Meanwhile, FVP affected the synthesis of short-chain fatty acids derived from gut microbiota. |
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| Keywords: | Fermentation Flammulina velutipes polysaccharides gut microbiota simulated digestion |
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